SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fy6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 2fy6 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		4 / 6 LEU A  37
VAL A  33
ILE A 145
ILE A  92
 None
 0.81A 2piwA-2fy6A:
undetectable		 2piwA-2fy6A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2fy6 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		4 / 5 LEU A  91
GLN A  76
THR A  77
LEU A 167
 None
SO4  A 315 ( 3.8A)
None
None
 1.25A 3ce6D-2fy6A:
undetectable		 3ce6D-2fy6A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2fy6 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		5 / 12 SER A  72
PRO A  68
GLY A 157
VAL A 155
ILE A 159
 None
 1.40A 3jb2A-2fy6A:
undetectable		 3jb2A-2fy6A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 2fy6 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		3 / 3 GLU A 161
PHE A  86
GLN A  76
 SO4  A 315 ( 3.8A)
None
SO4  A 315 ( 3.8A)
 0.91A 3r55A-2fy6A:
undetectable		 3r55A-2fy6A:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2fy6 PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		4 / 7 THR A  93
ALA A  95
THR A 124
VAL A 122
 None
 0.95A 4ik7A-2fy6A:
undetectable		 4ik7A-2fy6A:
21.56