SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fz1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fz1 COAT PROTEIN
(Turnip
yellow
mosaic
virus) 		4 / 6 THR A  81
GLY A  43
THR A  89
ILE A 157
 None
 0.91A 1gtnD-2fz1A:
undetectable
1gtnE-2fz1A:
undetectable		 1gtnD-2fz1A:
15.62
1gtnE-2fz1A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fz1 COAT PROTEIN
(Turnip
yellow
mosaic
virus) 		4 / 7 SER A 100
GLY A 113
THR A 110
ILE A 107
 None
 0.88A 1gtnF-2fz1A:
undetectable
1gtnG-2fz1A:
undetectable		 1gtnF-2fz1A:
15.62
1gtnG-2fz1A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2fz1 COAT PROTEIN
(Turnip
yellow
mosaic
virus) 		4 / 7 SER A 100
GLY A 113
THR A 110
ILE A 107
 None
 0.90A 1gtnJ-2fz1A:
undetectable
1gtnK-2fz1A:
undetectable		 1gtnJ-2fz1A:
15.62
1gtnK-2fz1A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 2fz1 COAT PROTEIN
(Turnip
yellow
mosaic
virus) 		5 / 12 GLY A 112
VAL A  76
GLY A  92
ILE A 115
VAL A 130
 None
 0.86A 3el5B-2fz1A:
undetectable		 3el5B-2fz1A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2fz1 COAT PROTEIN
(Turnip
yellow
mosaic
virus) 		5 / 12 ILE A 157
ILE A 118
ALA A  84
THR A  81
ALA A  42
 None
 1.11A 4enhA-2fz1A:
undetectable		 4enhA-2fz1A:
18.04