SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2fzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifA-2fzvA:
3.9		 1kifA-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifB-2fzvA:
3.9		 1kifB-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifC-2fzvA:
3.7		 1kifC-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifD-2fzvA:
3.9		 1kifD-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifE-2fzvA:
3.9		 1kifE-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifF-2fzvA:
3.9		 1kifF-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifG-2fzvA:
3.7		 1kifG-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.04A 1kifH-2fzvA:
2.1		 1kifH-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.02A 1ve9A-2fzvA:
3.7		 1ve9A-2fzvA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 6 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 0.95A 2du8B-2fzvA:
3.9		 2du8B-2fzvA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 1.00A 2du8G-2fzvA:
3.8		 2du8G-2fzvA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 5 TYR A 195
ILE A 198
ARG A 188
GLY A 187
 None
 0.99A 2du8J-2fzvA:
2.4		 2du8J-2fzvA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		3 / 3 ARG A 166
GLY A 162
SER A 100
 None
 0.66A 2xctB-2fzvA:
4.4		 2xctB-2fzvA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROP_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 6 TRP A 105
LEU A  38
SER A  97
THR A 135
 None
 1.45A 3ropA-2fzvA:
5.5		 3ropA-2fzvA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 7 ILE A 122
GLY A 162
THR A 157
TRP A 105
 None
 1.08A 4zxiA-2fzvA:
3.3		 4zxiA-2fzvA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 7 ILE A 122
ARG A 163
MET A 167
LEU A 140
 None
 0.93A 5b1aA-2fzvA:
undetectable
5b1aJ-2fzvA:
undetectable		 5b1aA-2fzvA:
19.96
5b1aJ-2fzvA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 7 ILE A 122
ARG A 163
MET A 167
LEU A 140
 None
 0.94A 5b3sA-2fzvA:
undetectable
5b3sJ-2fzvA:
undetectable		 5b3sA-2fzvA:
19.96
5b3sJ-2fzvA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		4 / 7 ILE A 122
ARG A 163
MET A 167
LEU A 140
 None
 0.89A 5zcpA-2fzvA:
undetectable
5zcpJ-2fzvA:
undetectable		 5zcpA-2fzvA:
19.96
5zcpJ-2fzvA:
10.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 2fzv PUTATIVE ARSENICAL
RESISTANCE PROTEIN
(Shigella
flexneri) 		3 / 3 ARG A  47
ARG A  59
ARG A  51
 None
 1.06A 6bplA-2fzvA:
undetectable
6bplB-2fzvA:
undetectable		 6bplA-2fzvA:
14.29
6bplB-2fzvA:
14.29