SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g02'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 GLY A 145
ALA A  92
THR A  84
ILE A 149
 None
 0.80A 1c9sI-2g02A:
undetectable
1c9sJ-2g02A:
undetectable		 1c9sI-2g02A:
9.83
1c9sJ-2g02A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CRB_A_RTLA200_0
(CELLULAR RETINOL
BINDING PROTEIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 LEU A  96
LEU A  39
ALA A 404
LEU A 405
ILE A 396
 None
 0.97A 1crbA-2g02A:
undetectable		 1crbA-2g02A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 7 GLY A 145
ALA A  92
THR A  84
ILE A 149
 None
 0.83A 1gtnA-2g02A:
undetectable
1gtnK-2g02A:
undetectable		 1gtnA-2g02A:
9.83
1gtnK-2g02A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 GLY A 145
ALA A  92
THR A  84
ILE A 149
 None
 0.83A 1gtnE-2g02A:
undetectable
1gtnF-2g02A:
undetectable		 1gtnE-2g02A:
9.83
1gtnF-2g02A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 6 TRP A 401
SER A 383
ASN A  13
SER A 390
 None
 1.15A 1kiaC-2g02A:
undetectable		 1kiaC-2g02A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NCW_H_BEZH601_0
(IMMUNOGLOBULIN IGG2A)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 9 ALA A 404
TRP A 401
LEU A  96
GLY A  93
GLY A  45
 None
 1.21A 1ncwH-2g02A:
undetectable
1ncwL-2g02A:
undetectable		 1ncwH-2g02A:
19.54
1ncwL-2g02A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUA_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 10 ALA A 404
TRP A 401
LEU A  96
GLY A  93
GLY A  45
 None
 1.21A 1ruaH-2g02A:
undetectable
1ruaL-2g02A:
undetectable		 1ruaH-2g02A:
19.54
1ruaL-2g02A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 8 ALA A 404
TRP A 401
LEU A  96
GLY A  93
GLY A  45
 None
 1.22A 1rukH-2g02A:
undetectable
1rukL-2g02A:
undetectable		 1rukH-2g02A:
19.54
1rukL-2g02A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUL_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 9 ALA A 404
TRP A 401
LEU A  96
GLY A  93
GLY A  45
 None
 1.25A 1rulH-2g02A:
undetectable
1rulL-2g02A:
undetectable		 1rulH-2g02A:
19.54
1rulL-2g02A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUP_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 9 ALA A 404
TRP A 401
LEU A  96
GLY A  93
GLY A  45
 None
 1.20A 1rupH-2g02A:
undetectable
1rupL-2g02A:
undetectable		 1rupH-2g02A:
19.54
1rupL-2g02A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 LEU A 292
CYH A 219
ALA A 222
LEU A 346
PHE A 408
 None
 1.15A 1s9pB-2g02A:
undetectable		 1s9pB-2g02A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 LEU A 405
CYH A 385
GLY A 384
PHE A 359
 None
 0.74A 1sv9A-2g02A:
undetectable		 1sv9A-2g02A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 GLY A 145
ALA A  92
THR A  84
ILE A 149
 None
 0.79A 1utdB-2g02A:
undetectable
1utdC-2g02A:
undetectable		 1utdB-2g02A:
9.83
1utdC-2g02A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 GLY A 145
ALA A  92
THR A  84
ILE A 149
 None
 0.81A 1utdF-2g02A:
undetectable
1utdG-2g02A:
undetectable		 1utdF-2g02A:
9.83
1utdG-2g02A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 GLY A 145
ALA A  92
THR A  84
ILE A 149
 None
 0.78A 1utdI-2g02A:
undetectable
1utdJ-2g02A:
undetectable		 1utdI-2g02A:
9.83
1utdJ-2g02A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 GLY A 145
ALA A  92
THR A  84
ILE A 149
 None
 0.80A 1utdJ-2g02A:
undetectable
1utdK-2g02A:
undetectable		 1utdJ-2g02A:
9.83
1utdK-2g02A:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 6 SER A 234
ILE A 169
ALA A 224
ALA A 300
 None
 0.85A 1w0gA-2g02A:
undetectable		 1w0gA-2g02A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 4 LEU A 214
LEU A 175
SER A 173
LEU A 221
 None
 1.17A 1ya3A-2g02A:
undetectable		 1ya3A-2g02A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_A_RBFA300_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 11 GLY A 148
SER A 147
LEU A 172
ILE A 119
ALA A  92
 None
 1.33A 2a58A-2g02A:
undetectable
2a58E-2g02A:
undetectable		 2a58A-2g02A:
17.20
2a58E-2g02A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_D_RBFD303_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 11 ILE A 119
ALA A  92
GLY A 148
SER A 147
LEU A 172
 None
 1.34A 2a58C-2g02A:
undetectable
2a58D-2g02A:
undetectable		 2a58C-2g02A:
17.20
2a58D-2g02A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 LEU A  48
GLU A  52
LEU A 407
LEU A 387
VAL A 388
 None
 1.07A 2c12C-2g02A:
undetectable		 2c12C-2g02A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 PHE A  34
ILE A  98
GLY A  93
SER A  86
ILE A  94
 None
 1.23A 2e7fA-2g02A:
undetectable		 2e7fA-2g02A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 PHE A  34
ILE A  98
GLY A  93
SER A  86
ILE A  94
 None
 1.26A 2e7fB-2g02A:
undetectable		 2e7fB-2g02A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		3 / 3 ASN A 362
ILE A 324
MET A 318
 None
 0.86A 2h42C-2g02A:
undetectable		 2h42C-2g02A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 PHE A  34
ILE A  98
GLY A  93
SER A  86
ILE A  94
 None
 1.21A 2ogyA-2g02A:
undetectable		 2ogyA-2g02A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 PHE A  34
ILE A  98
GLY A  93
SER A  86
ILE A  94
 None
 1.24A 2ogyB-2g02A:
undetectable		 2ogyB-2g02A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 PHE A  34
LEU A  48
GLY A  93
SER A  86
ILE A  94
 None
 1.36A 2ogyB-2g02A:
undetectable		 2ogyB-2g02A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA504_0
(CHORISMATE SYNTHASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 5 SER A 230
HIS A 225
LEU A 238
SER A 234
 None
 1.18A 2qhfA-2g02A:
undetectable		 2qhfA-2g02A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 7 ILE A 220
LEU A 155
LEU A  87
GLY A 148
 None
 0.94A 2qqcD-2g02A:
undetectable
2qqcE-2g02A:
undetectable		 2qqcD-2g02A:
15.69
2qqcE-2g02A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 GLY A  42
GLY A 384
GLY A 381
GLU A 380
VAL A 388
 None
 1.18A 2wa2A-2g02A:
undetectable		 2wa2A-2g02A:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 6 LEU A 175
THR A 176
LEU A 214
ASP A 141
 None
 1.06A 2wm3A-2g02A:
undetectable		 2wm3A-2g02A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 PHE A  34
ILE A  98
GLY A  93
SER A  86
ILE A  94
 None
 1.28A 2ycjA-2g02A:
undetectable		 2ycjA-2g02A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 ILE A 290
LEU A 293
ILE A 313
ILE A 241
VAL A 272
 None
 1.05A 2ygnA-2g02A:
undetectable		 2ygnA-2g02A:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 7 ILE A  66
ILE A  47
SER A  97
THR A 399
 None
 0.81A 3deuA-2g02A:
undetectable		 3deuA-2g02A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DXY_A_SAMA1_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 11 GLY A 216
GLY A 213
ILE A 220
VAL A 142
HIS A 212
 None
 0.95A 3dxyA-2g02A:
undetectable		 3dxyA-2g02A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 ILE A  94
PRO A  44
SER A  86
GLY A  93
 None
 0.96A 3lslA-2g02A:
undetectable
3lslD-2g02A:
undetectable		 3lslA-2g02A:
21.90
3lslD-2g02A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 6 TYR A 296
CYH A 219
VAL A 142
PHE A 408
 None
 1.10A 3ltwA-2g02A:
undetectable		 3ltwA-2g02A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 6 THR A  41
GLY A 377
ILE A  46
LEU A  39
 None
 1.04A 4acbC-2g02A:
undetectable		 4acbC-2g02A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		3 / 3 ARG A 345
THR A 399
TRP A 401
 None
 1.16A 4d7hA-2g02A:
undetectable		 4d7hA-2g02A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 PHE A  34
ILE A  98
GLY A  93
SER A  86
ILE A  94
 None
 1.30A 4djfA-2g02A:
undetectable		 4djfA-2g02A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 7 LEU A  39
TYR A  88
ILE A 329
GLY A 377
 None
 0.78A 4eq4A-2g02A:
undetectable		 4eq4A-2g02A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 LEU A  39
TYR A  88
ILE A 329
GLY A 377
 None
 0.77A 4eq4B-2g02A:
undetectable		 4eq4B-2g02A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 7 LEU A  39
TYR A  88
ILE A 329
GLY A 377
 None
 0.77A 4eqlA-2g02A:
undetectable		 4eqlA-2g02A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 7 LEU A  39
TYR A  88
ILE A 329
GLY A 377
 None
 0.76A 4eqlB-2g02A:
undetectable		 4eqlB-2g02A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 6 LEU A  39
TYR A  88
ILE A 329
GLY A 377
 None
 0.68A 4l39A-2g02A:
undetectable		 4l39A-2g02A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 7 LEU A  39
TYR A  88
ILE A 329
GLY A 377
 None
 0.73A 4l39B-2g02A:
undetectable		 4l39B-2g02A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		3 / 3 ARG A 345
THR A 399
TRP A 401
 None
 1.19A 4ug5A-2g02A:
undetectable		 4ug5A-2g02A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		3 / 3 ARG A 345
THR A 399
TRP A 401
 None
 1.22A 4uglA-2g02A:
undetectable		 4uglA-2g02A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 GLY A 287
LEU A 292
LEU A 322
ILE A 279
GLY A 216
 None
 0.98A 5d4uC-2g02A:
undetectable		 5d4uC-2g02A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 GLY A 287
LEU A 292
LEU A 322
ILE A 279
GLY A 216
 None
 0.94A 5d4uD-2g02A:
undetectable		 5d4uD-2g02A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		4 / 8 TYR A  88
LEU A  39
GLY A 384
LEU A 405
 None
 0.85A 5eseA-2g02A:
undetectable		 5eseA-2g02A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		3 / 3 ARG A 345
THR A 399
TRP A 401
 None
 1.16A 5g6cA-2g02A:
undetectable		 5g6cA-2g02A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 10 GLY A  93
GLY A  90
SER A  86
LEU A  87
GLU A 144
 None
 1.33A 5hwkA-2g02A:
undetectable		 5hwkA-2g02A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 10 GLY A  93
GLY A  90
SER A  86
LEU A  87
GLU A 144
 None
 1.34A 5hwkB-2g02A:
undetectable		 5hwkB-2g02A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 ILE A 339
GLY A 287
ALA A 211
SER A 326
ILE A 324
 None
 1.11A 5ih0A-2g02A:
undetectable		 5ih0A-2g02A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 12 TYR A 285
GLY A 261
GLY A 209
ASP A 265
ASP A 260
 None
 1.28A 5ynmA-2g02A:
undetectable		 5ynmA-2g02A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 10 LEU A 412
VAL A 307
TYR A 296
GLY A 298
LEU A 346
 None
 1.36A 6bsiA-2g02A:
undetectable		 6bsiA-2g02A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 10 LEU A 412
VAL A 307
TYR A 296
GLY A 298
LEU A 346
 None
 1.36A 6bsjA-2g02A:
undetectable		 6bsjA-2g02A:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2g02 NISIN BIOSYNTHESIS
PROTEIN NISC
(Lactococcus
lactis) 		5 / 10 LEU A  77
ILE A  94
PRO A  44
SER A  89
GLY A  93
 None
 1.21A 6dm0B-2g02A:
undetectable
6dm0C-2g02A:
2.8		 6dm0B-2g02A:
13.41
6dm0C-2g02A:
13.41