SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g0f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		5 / 12 LEU A  72
ILE A 149
VAL A  75
LEU A 134
LEU A 138
 None
 1.02A 1s19A-2g0fA:
undetectable		 1s19A-2g0fA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		5 / 12 LEU A  72
VAL A  71
ILE A 149
LEU A 134
LEU A 138
 None
 1.00A 1s19A-2g0fA:
undetectable		 1s19A-2g0fA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		4 / 5 GLY A 139
PRO A  46
VAL A  45
ILE A 155
 None
 0.90A 2aoiA-2g0fA:
undetectable		 2aoiA-2g0fA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		5 / 12 LEU A  90
ASN A  91
LEU A  93
VAL A  71
LEU A 116
 None
 1.11A 2oz7A-2g0fA:
undetectable		 2oz7A-2g0fA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		5 / 11 GLY A 139
VAL A 140
PRO A  46
VAL A  45
ILE A 155
 None
 1.11A 3oxxB-2g0fA:
undetectable		 3oxxB-2g0fA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_2
(GUANINE DEAMINASE)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		4 / 5 HIS A  87
LEU A 127
LEU A  73
ASP A 129
 None
 1.33A 4aqlA-2g0fA:
undetectable		 4aqlA-2g0fA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		4 / 6 VAL A 101
VAL A  71
ILE A 149
LEU A 138
 None
 0.98A 4l1wB-2g0fA:
undetectable		 4l1wB-2g0fA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		5 / 12 GLY A 139
ASP A 129
MET A 103
GLY A 132
TYR A 105
 None
 0.97A 4qa2A-2g0fA:
undetectable		 4qa2A-2g0fA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		3 / 3 HIS A  87
GLU A  86
TRP A  76
 None
 1.09A 5odiD-2g0fA:
undetectable		 5odiD-2g0fA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		3 / 3 HIS A  87
GLU A  86
TRP A  76
 None
 1.13A 5odrD-2g0fA:
undetectable		 5odrD-2g0fA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		3 / 3 VAL A  64
TYR A  60
GLN A  61
 None
 0.70A 5qgkA-2g0fA:
undetectable		 5qgkA-2g0fA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		3 / 3 VAL A  64
TYR A  60
GLN A  61
 None
 0.65A 5qgrA-2g0fA:
undetectable		 5qgrA-2g0fA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2g0f THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBE
(Escherichia
coli) 		3 / 3 VAL A  64
TYR A  60
GLN A  61
 None
 0.67A 5qgtA-2g0fA:
undetectable		 5qgtA-2g0fA:
23.70