SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g0j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_2 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	2g0j	HYPOTHETICAL PROTEIN SMU.848 (Streptococcus mutans)	4 / 4	THR A 19 LEU A 18 VAL A 36 LEU A 39	None	0.96A	1fbmD-2g0jA: undetectable	1fbmD-2g0jA: 16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_A_CELA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	2g0j	HYPOTHETICAL PROTEIN SMU.848 (Streptococcus mutans)	5 / 12	VAL A 32 SER A 40 ILE A 93 ALA A 97 SER A 100	None	1.13A	3kk6A-2g0jA: undetectable	3kk6A-2g0jA: 12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8Y_B_DIFB585_1 (PROSTAGLANDIN G/H SYNTHASE 1)	2g0j	HYPOTHETICAL PROTEIN SMU.848 (Streptococcus mutans)	5 / 12	VAL A 32 VAL A 36 LEU A 39 SER A 40 ALA A 4	None	1.07A	3n8yB-2g0jA: undetectable	3n8yB-2g0jA: 12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UYM_A_VORA590_1 (14-ALPHA STEROL DEMETHYLASE)	2g0j	HYPOTHETICAL PROTEIN SMU.848 (Streptococcus mutans)	4 / 7	ALA A 34 SER A 37 ILE A 2 LEU A 96	None	0.92A	4uymA-2g0jA: undetectable	4uymA-2g0jA: 14.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FBM_B_RTLB951_2","PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN)","2g0j","HYPOTHETICAL PROTEIN SMU.848","Streptococcus mutans",4,"THR A  19;LEU A  18;VAL A  36;LEU A  39","None","0.96A","1fbmD-2g0jA:undetectable","1fbmD-2g0jA:16.20"],["3KK6_A_CELA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","2g0j","HYPOTHETICAL PROTEIN SMU.848","Streptococcus mutans",5,"VAL A  32;SER A  40;ILE A  93;ALA A  97;SER A 100","None","1.13A","3kk6A-2g0jA:undetectable","3kk6A-2g0jA:12.20"],["3N8Y_B_DIFB585_1","PROSTAGLANDIN G\/H SYNTHASE 1","2g0j","HYPOTHETICAL PROTEIN SMU.848","Streptococcus mutans",5,"VAL A  32;VAL A  36;LEU A  39;SER A  40;ALA A   4","None","1.07A","3n8yB-2g0jA:undetectable","3n8yB-2g0jA:12.20"],["4UYM_A_VORA590_1","14-ALPHA STEROL DEMETHYLASE","2g0j","HYPOTHETICAL PROTEIN SMU.848","Streptococcus mutans",4,"ALA A  34;SER A  37;ILE A   2;LEU A  96","None","0.92A","4uymA-2g0jA:undetectable","4uymA-2g0jA:14.26"]]