SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g0w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 12 PHE A 105
LEU A  43
PHE A  26
HIS A 100
ASP A  58
 None
 1.36A 1a4lB-2g0wA:
3.0		 1a4lB-2g0wA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 10 HIS A 109
VAL A 244
LEU A 137
GLY A 106
ALA A 102
 None
 1.07A 2xf3A-2g0wA:
undetectable		 2xf3A-2g0wA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 9 HIS A 109
VAL A 244
LEU A 137
GLY A 106
ALA A 102
 None
 1.04A 2xf3B-2g0wA:
undetectable		 2xf3B-2g0wA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 8 HIS A 109
VAL A 244
LEU A 137
GLY A 106
ALA A 102
 None
 1.07A 2xfsA-2g0wA:
undetectable		 2xfsA-2g0wA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 9 HIS A 109
VAL A 244
LEU A 137
GLY A 106
ALA A 102
 None
 1.06A 2xfsB-2g0wA:
undetectable		 2xfsB-2g0wA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 8 HIS A 109
VAL A 244
LEU A 137
GLY A 106
ALA A 102
 None
 1.06A 2xh9A-2g0wA:
undetectable		 2xh9A-2g0wA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 9 HIS A 109
VAL A 244
LEU A 137
GLY A 106
ALA A 102
 None
 1.04A 2xh9B-2g0wA:
undetectable		 2xh9B-2g0wA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		4 / 5 ARG A 218
ASP A 172
ILE A 170
GLU A 248
 MG  A 501 ( 4.1A)
MG  A 501 (-3.2A)
None
MG  A 501 (-2.8A)
 1.25A 2xrzA-2g0wA:
undetectable
2xrzB-2g0wA:
undetectable		 2xrzA-2g0wA:
20.45
2xrzB-2g0wA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		3 / 3 TYR A  18
GLU A  76
THR A  79
 None
 0.98A 2y7hB-2g0wA:
undetectable		 2y7hB-2g0wA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		3 / 3 TRP A 174
ALA A 220
VAL A 202
 None
 0.93A 3l8lA-2g0wA:
undetectable
3l8lB-2g0wA:
undetectable		 3l8lA-2g0wA:
6.35
3l8lB-2g0wA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 173
LEU A 152
VAL A 240
ILE A 197
SER A 196
 None
 1.30A 4lhmA-2g0wA:
undetectable		 4lhmA-2g0wA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		5 / 12 LEU A 115
ARG A 211
SER A 147
GLU A 142
TYR A  77
 None
None
None
MG  A 501 (-2.5A)
None
 1.41A 4mx0A-2g0wA:
undetectable		 4mx0A-2g0wA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		4 / 5 GLU A 248
GLU A  74
ASN A 111
GLU A 142
 MG  A 501 (-2.8A)
None
None
MG  A 501 (-2.5A)
 1.32A 5dwkC-2g0wA:
undetectable		 5dwkC-2g0wA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		4 / 6 ALA A 269
THR A 270
VAL A 273
VAL A 249
 None
 0.98A 5eckA-2g0wA:
undetectable		 5eckA-2g0wA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		4 / 6 ALA A 269
THR A 270
VAL A 273
VAL A 249
 None
 0.91A 5eclD-2g0wA:
undetectable		 5eclD-2g0wA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ALA A 269
THR A 270
VAL A 273
VAL A 249
 None
 0.84A 5ecoD-2g0wA:
undetectable		 5ecoD-2g0wA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 2g0w LMO2234 PROTEIN
(Listeria
monocytogenes) 		4 / 5 GLU A  74
HIS A 109
LEU A 169
VAL A 195
 None
 1.17A 6bc9A-2g0wA:
undetectable		 6bc9A-2g0wA:
15.68