SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g16'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 2g16 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		3 / 3 ASN B 170
LEU B 141
HIS B 169
 None
 0.85A 2q6fB-2g16B:
undetectable		 2q6fB-2g16B:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2g16 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 12 LEU B 137
GLY B 138
GLN B 177
ILE B 171
ASP B 173
 None
 1.20A 6bxnB-2g16B:
undetectable		 6bxnB-2g16B:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2g16 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 SER B  86
LEU B 201
SER B  72
ILE B 152
PRO B 196
 None
 1.50A 6dm1B-2g16B:
undetectable
6dm1C-2g16B:
undetectable		 6dm1B-2g16B:
18.45
6dm1C-2g16B:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2g16 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 SER B  86
LEU B 201
SER B  72
ILE B 152
PRO B 196
 None
 1.49A 6dm2B-2g16B:
undetectable
6dm2C-2g16B:
undetectable		 6dm2B-2g16B:
18.45
6dm2C-2g16B:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2g16 GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 ILE B 152
PRO B 196
SER B  86
LEU B 201
SER B  72
 None
 1.50A 6dm2A-2g16B:
undetectable
6dm2D-2g16B:
undetectable		 6dm2A-2g16B:
18.45
6dm2D-2g16B:
18.45