SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g17'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 LEU A 166
LEU A 171
GLY A 170
ALA A 224
LEU A 222
 None
 1.18A 1gs4A-2g17A:
undetectable		 1gs4A-2g17A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_A_DOLA300_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 11 ILE A 218
PRO A 152
LEU A 135
VAL A 283
ASP A 290
 None
 1.38A 1mrlA-2g17A:
0.0
1mrlB-2g17A:
0.0		 1mrlA-2g17A:
20.41
1mrlB-2g17A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 6 ASP A 307
GLY A 238
PRO A 236
SER A 187
 None
 0.94A 1n4fA-2g17A:
undetectable		 1n4fA-2g17A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 7 ARG A 213
ILE A 218
PRO A 156
GLU A 217
 SO4  A 410 (-3.0A)
None
None
None
 0.99A 1oniA-2g17A:
undetectable
1oniB-2g17A:
undetectable		 1oniA-2g17A:
19.53
1oniB-2g17A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 6 ARG A 213
ILE A 218
PRO A 156
GLU A 217
 SO4  A 410 (-3.0A)
None
None
None
 0.95A 1oniB-2g17A:
undetectable
1oniC-2g17A:
undetectable		 1oniB-2g17A:
19.53
1oniC-2g17A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 6 ILE A 218
PRO A 156
GLU A 217
ARG A 213
 None
None
None
SO4  A 410 (-3.0A)
 1.07A 1oniA-2g17A:
undetectable
1oniC-2g17A:
undetectable		 1oniA-2g17A:
19.53
1oniC-2g17A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 7 ILE A 218
PRO A 156
GLU A 217
ARG A 213
 None
None
None
SO4  A 410 (-3.0A)
 0.98A 1oniD-2g17A:
undetectable
1oniE-2g17A:
undetectable		 1oniD-2g17A:
19.53
1oniE-2g17A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_G_BEZG513_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 5 ARG A 213
ILE A 218
PRO A 156
GLU A 217
 SO4  A 410 (-3.0A)
None
None
None
 1.00A 1oniG-2g17A:
0.0
1oniH-2g17A:
0.0		 1oniG-2g17A:
19.53
1oniH-2g17A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 7 ILE A 218
PRO A 156
GLU A 217
ARG A 213
 None
None
None
SO4  A 410 (-3.0A)
 0.96A 1oniG-2g17A:
undetectable
1oniI-2g17A:
undetectable		 1oniG-2g17A:
19.53
1oniI-2g17A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 10 VAL A 256
ILE A 291
GLY A 292
ILE A 301
LEU A 300
 None
 1.08A 1z11D-2g17A:
undetectable		 1z11D-2g17A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 5 LEU A 310
ASP A 307
GLY A 188
ALA A 314
 None
 0.92A 2aohA-2g17A:
undetectable		 2aohA-2g17A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 LEU A  52
GLY A  11
ARG A 237
ALA A  13
ALA A 313
 None
SO4  A 405 (-3.1A)
None
SO4  A 405 (-3.7A)
None
 1.15A 2bm9A-2g17A:
4.0		 2bm9A-2g17A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 7 TYR A 207
TYR A 118
GLU A 217
GLY A 153
 SO4  A 410 ( 4.7A)
SO4  A 402 (-4.4A)
None
SO4  A 406 (-3.4A)
 1.18A 2ha4B-2g17A:
undetectable		 2ha4B-2g17A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		6 / 12 GLY A 190
LEU A  17
GLY A  14
GLY A  11
LEU A 309
LEU A 102
 SO4  A 405 (-3.3A)
None
None
SO4  A 405 (-3.1A)
None
None
 1.28A 2nxeA-2g17A:
4.3		 2nxeA-2g17A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 5 SER A 184
PHE A 235
VAL A 202
TYR A 155
 None
 1.37A 2x7hA-2g17A:
3.1		 2x7hA-2g17A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1372_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 5 SER A 184
PHE A 235
VAL A 202
TYR A 155
 None
 1.35A 2x7hB-2g17A:
4.9		 2x7hB-2g17A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 8 VAL A 318
SER A  85
TYR A  20
VAL A 151
 None
 1.33A 2y05A-2g17A:
4.7
2y05B-2g17A:
4.7		 2y05A-2g17A:
23.26
2y05B-2g17A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 7 LEU A 280
ARG A 237
SER A 162
GLY A 312
 None
 1.02A 3hcrB-2g17A:
undetectable		 3hcrB-2g17A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 GLY A 312
ALA A 313
ALA A 158
ASP A 307
ILE A 239
 None
 1.12A 3id6C-2g17A:
undetectable		 3id6C-2g17A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 GLU A  16
LEU A 309
ARG A 237
ARG A  23
TYR A  20
 None
 1.48A 3k39O-2g17A:
undetectable		 3k39O-2g17A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		3 / 3 ARG A 324
VAL A  21
THR A   4
 None
 0.72A 3ndtA-2g17A:
undetectable		 3ndtA-2g17A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 LEU A   5
THR A   4
ALA A   9
ALA A  79
LEU A  58
 None
 1.17A 3p5nA-2g17A:
undetectable		 3p5nA-2g17A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 LEU A   5
THR A   4
ALA A   9
ALA A  79
LEU A  58
 None
 1.17A 3p5nB-2g17A:
undetectable		 3p5nB-2g17A:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 ARG A 237
GLY A 188
SER A 103
GLU A  16
ALA A 313
 None
None
SO4  A 402 (-3.7A)
None
None
 1.25A 3t7sB-2g17A:
3.7		 3t7sB-2g17A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 ARG A 237
GLY A 188
SER A 103
GLU A  16
ALA A 313
 None
None
SO4  A 402 (-3.7A)
None
None
 1.27A 3t7sD-2g17A:
4.2		 3t7sD-2g17A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		6 / 12 LEU A  48
GLY A  14
ALA A  15
VAL A  56
PRO A  59
ILE A  45
 None
 1.42A 3tl9B-2g17A:
undetectable		 3tl9B-2g17A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		3 / 3 LYS A 267
PRO A 268
LEU A 269
 SO4  A 404 (-2.8A)
None
None
 0.74A 3tpxE-2g17A:
undetectable		 3tpxE-2g17A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 12 ALA A 159
GLY A 312
GLY A 153
LEU A 102
ALA A 158
 None
None
SO4  A 406 (-3.4A)
None
None
 1.12A 4lg1C-2g17A:
undetectable		 4lg1C-2g17A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 8 LEU A 172
LYS A 248
VAL A 251
LEU A 300
 None
 1.14A 4q0bA-2g17A:
undetectable		 4q0bA-2g17A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA305_0
(THAUMATIN-1)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 5 GLU A 241
ILE A 180
PHE A 228
VAL A 226
 None
 1.50A 4tvtA-2g17A:
0.0		 4tvtA-2g17A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 6 ILE A 218
GLN A 160
ILE A 167
ASP A 168
 None
 1.17A 4w5qA-2g17A:
2.8		 4w5qA-2g17A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 6 ILE A 218
GLN A 160
ILE A 167
ASP A 168
 None
 1.15A 4z4cA-2g17A:
2.8		 4z4cA-2g17A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 6 GLY A 238
ASP A 307
ARG A 237
GLY A 185
 None
 0.99A 5cdpA-2g17A:
undetectable
5cdpB-2g17A:
undetectable		 5cdpA-2g17A:
22.29
5cdpB-2g17A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		3 / 3 TYR A  12
TYR A 207
SER A 184
 SO4  A 405 (-4.6A)
SO4  A 410 ( 4.7A)
None
 0.82A 5iktB-2g17A:
undetectable		 5iktB-2g17A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		5 / 7 LEU A 102
GLY A  14
GLY A  11
SER A 103
ALA A 313
 None
None
SO4  A 405 (-3.1A)
SO4  A 402 (-3.7A)
None
 1.06A 5o96C-2g17A:
undetectable		 5o96C-2g17A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 2g17 N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE
REDUCTASE
(Salmonella
enterica) 		4 / 8 GLY A  14
LEU A  17
THR A  33
VAL A  76
 None
 0.86A 6czmD-2g17A:
0.7
6czmF-2g17A:
1.0		 6czmD-2g17A:
23.74
6czmF-2g17A:
23.74