SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g18'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		3 / 3 LEU A  39
PRO A  40
LEU A  43
 None
 0.37A 1hrkA-2g18A:
undetectable		 1hrkA-2g18A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		3 / 3 LEU A 174
VAL A 177
LEU A 181
 None
 0.47A 1mz9B-2g18A:
undetectable		 1mz9B-2g18A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 12 TYR A 130
ILE A 202
VAL A 194
SER A 129
HIS A 184
 None
 1.31A 1nbhA-2g18A:
undetectable		 1nbhA-2g18A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 12 TYR A 130
ILE A 202
VAL A 194
SER A 129
HIS A 184
 None
 1.30A 1nbhC-2g18A:
undetectable		 1nbhC-2g18A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 12 TYR A 130
ILE A 202
VAL A 194
SER A 129
HIS A 184
 None
 1.29A 1nbhD-2g18A:
undetectable		 1nbhD-2g18A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 12 THR A  64
GLN A  66
ILE A 202
VAL A 120
ALA A 188
 None
 1.29A 2g72B-2g18A:
undetectable		 2g72B-2g18A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 5 SER A 166
ARG A 176
GLY A 175
GLU A 179
 None
 1.18A 3k9fA-2g18A:
undetectable
3k9fB-2g18A:
undetectable
3k9fC-2g18A:
undetectable		 3k9fA-2g18A:
19.43
3k9fB-2g18A:
19.43
3k9fC-2g18A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 8 SER A 118
PHE A  99
LEU A 103
ASP A 102
 None
 1.06A 3m0wE-2g18A:
undetectable
3m0wF-2g18A:
undetectable
3m0wG-2g18A:
undetectable
3m0wH-2g18A:
undetectable		 3m0wE-2g18A:
18.03
3m0wF-2g18A:
18.03
3m0wG-2g18A:
18.03
3m0wH-2g18A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		3 / 3 HIS A 121
SER A 156
ASN A 131
 None
 0.87A 3s8pB-2g18A:
undetectable		 3s8pB-2g18A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		3 / 3 LEU A  39
PRO A  40
LEU A  43
 None
 0.45A 3w1wB-2g18A:
undetectable		 3w1wB-2g18A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 5 LEU A 223
HIS A  85
GLU A  73
HIS A  71
 None
 1.25A 4a7bB-2g18A:
undetectable		 4a7bB-2g18A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 7 SER A 118
GLN A 213
TYR A 209
ASP A 102
 None
 1.11A 4hxyB-2g18A:
undetectable		 4hxyB-2g18A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 10 LEU A 240
LEU A  72
LEU A  84
ILE A  83
LEU A 223
 None
 1.05A 4odoA-2g18A:
undetectable		 4odoA-2g18A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 10 LEU A 240
LEU A  72
LEU A  84
ILE A  83
LEU A 223
 None
 1.01A 4odoB-2g18A:
undetectable		 4odoB-2g18A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 10 LEU A 240
LEU A  72
LEU A  84
ILE A  83
LEU A 223
 None
 1.04A 4odoC-2g18A:
undetectable		 4odoC-2g18A:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 10 LEU A  84
LEU A  20
ALA A  21
LEU A 181
LEU A  72
 None
 1.23A 4p65A-2g18A:
undetectable
4p65B-2g18A:
undetectable
4p65F-2g18A:
undetectable
4p65H-2g18A:
undetectable		 4p65A-2g18A:
6.70
4p65B-2g18A:
10.00
4p65F-2g18A:
10.00
4p65H-2g18A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		5 / 12 ASN A 208
GLY A 205
GLN A 206
ARG A  68
GLN A 215
 None
 1.34A 4p6xK-2g18A:
undetectable		 4p6xK-2g18A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YBN_A_ACTA303_0
(FLAVIN-NUCLEOTIDE-BI
NDING PROTEIN)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		3 / 3 VAL A 183
TYR A 130
ALA A 133
 None
 0.55A 4ybnA-2g18A:
undetectable		 4ybnA-2g18A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 5 ARG A 176
GLY A 175
GLU A 179
SER A 166
 None
 1.21A 4z3oA-2g18A:
undetectable
4z3oB-2g18A:
undetectable		 4z3oA-2g18A:
17.80
4z3oB-2g18A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 7 SER A 166
ARG A 176
GLY A 175
GLU A 179
 None
 0.91A 5btaA-2g18A:
undetectable
5btaC-2g18A:
undetectable
5btaD-2g18A:
undetectable		 5btaA-2g18A:
20.24
5btaC-2g18A:
20.24
5btaD-2g18A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 6 SER A 166
ARG A 176
GLY A 175
GLU A 179
 None
 0.95A 5btaA-2g18A:
undetectable
5btaB-2g18A:
undetectable
5btaC-2g18A:
undetectable		 5btaA-2g18A:
20.24
5btaB-2g18A:
22.38
5btaC-2g18A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 6 SER A 166
ARG A 176
GLY A 175
GLU A 179
 None
 0.90A 5btcA-2g18A:
1.3
5btcC-2g18A:
undetectable
5btcD-2g18A:
undetectable		 5btcA-2g18A:
20.24
5btcC-2g18A:
20.24
5btcD-2g18A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 6 SER A 166
ARG A 176
GLY A 175
GLU A 179
 None
 0.92A 5btcA-2g18A:
1.3
5btcB-2g18A:
undetectable
5btcC-2g18A:
undetectable		 5btcA-2g18A:
20.24
5btcB-2g18A:
22.38
5btcC-2g18A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 7 SER A 166
ARG A 176
GLY A 175
GLU A 179
 None
 0.93A 5btfA-2g18A:
undetectable
5btfB-2g18A:
undetectable
5btfC-2g18A:
undetectable		 5btfA-2g18A:
20.24
5btfB-2g18A:
22.38
5btfC-2g18A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		3 / 3 HIS A 121
SER A 156
ASN A 131
 None
 0.87A 5cprB-2g18A:
undetectable		 5cprB-2g18A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2g18 PHYCOCYANOBILIN:FERR
EDOXIN
OXIDOREDUCTASE
(Anabaena
sp.) 		4 / 9 ILE A  57
VAL A 222
THR A 219
ILE A  83
 None
 1.00A 5lg3I-2g18A:
undetectable		 5lg3I-2g18A:
20.97