SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 8 GLU A  60
ASP A 119
ARG A 274
MET A 273
 None
 1.21A 1dtlA-2g29A:
undetectable		 1dtlA-2g29A:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		3 / 3 ALA A 407
VAL A 405
TRP A 352
 None
 0.79A 1micA-2g29A:
undetectable
1micB-2g29A:
undetectable		 1micA-2g29A:
5.65
1micB-2g29A:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 7 LEU A 289
GLU A 398
ALA A 400
ALA A 148
 None
 0.98A 1sn0B-2g29A:
undetectable
1sn0D-2g29A:
undetectable		 1sn0B-2g29A:
17.18
1sn0D-2g29A:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_P1ZA2002_1
(SERUM ALBUMIN)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 12 LEU A 175
LEU A 204
ILE A 200
ILE A 157
ALA A 256
 None
 1.02A 2bxqA-2g29A:
undetectable		 2bxqA-2g29A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		3 / 3 TRP A 243
LYS A 269
PRO A 222
 None
NO3  A 700 (-2.8A)
NO3  A 700 (-3.7A)
 1.46A 2dqyB-2g29A:
undetectable		 2dqyB-2g29A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 6 TRP A 102
HIS A 122
ASN A 151
GLN A 349
 NO3  A 700 (-3.8A)
None
None
None
 1.47A 2ez7A-2g29A:
undetectable		 2ez7A-2g29A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 6 ARG A 106
GLY A 103
PRO A 192
THR A 190
 None
None
None
NO3  A 700 (-3.9A)
 1.37A 2m2oB-2g29A:
undetectable		 2m2oB-2g29A:
5.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 5 GLN A 255
PHE A 335
PHE A 342
GLY A 260
 None
 1.18A 2qmzA-2g29A:
undetectable
2qmzB-2g29A:
undetectable		 2qmzA-2g29A:
19.46
2qmzB-2g29A:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 10 MET A 209
ALA A 180
ALA A 178
LEU A 159
VAL A 168
 None
 1.24A 2wuzA-2g29A:
undetectable		 2wuzA-2g29A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 10 MET A 209
ALA A 180
ALA A 178
LEU A 159
VAL A 168
 None
 1.24A 2wuzB-2g29A:
undetectable		 2wuzB-2g29A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 12 GLN A 250
GLY A 156
SER A 236
LEU A 257
ALA A 256
 None
 1.18A 3d91A-2g29A:
undetectable		 3d91A-2g29A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_2
(ADENOSYLHOMOCYSTEINA
SE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 4 GLN A 246
THR A 247
THR A 190
HIS A 196
 None
None
NO3  A 700 (-3.9A)
NO3  A 700 (-3.6A)
 1.49A 3g1uA-2g29A:
undetectable		 3g1uA-2g29A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 5 GLN A 246
THR A 247
THR A 190
HIS A 196
 None
None
NO3  A 700 (-3.9A)
NO3  A 700 (-3.6A)
 1.50A 3g1uC-2g29A:
undetectable		 3g1uC-2g29A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 5 GLN A 246
THR A 247
THR A 190
HIS A 196
 None
None
NO3  A 700 (-3.9A)
NO3  A 700 (-3.6A)
 1.49A 3glqA-2g29A:
undetectable		 3glqA-2g29A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 5 GLN A 246
THR A 247
THR A 190
HIS A 196
 None
None
NO3  A 700 (-3.9A)
NO3  A 700 (-3.6A)
 1.49A 3glqB-2g29A:
undetectable		 3glqB-2g29A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		3 / 3 CYH A 309
PRO A 321
ASP A 327
 None
 0.84A 3hlwB-2g29A:
undetectable		 3hlwB-2g29A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 6 PHE A 342
TYR A 333
THR A 259
PHE A 335
 None
 1.38A 3ltwA-2g29A:
undetectable		 3ltwA-2g29A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 6 LEU A 245
GLU A 241
PRO A 242
ARG A 328
 None
 1.41A 3ltwA-2g29A:
undetectable		 3ltwA-2g29A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 5 GLN A 246
THR A 247
THR A 190
HIS A 196
 None
None
NO3  A 700 (-3.9A)
NO3  A 700 (-3.6A)
 1.49A 3n58A-2g29A:
undetectable		 3n58A-2g29A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		3 / 3 LYS A 140
ARG A 106
LYS A  65
 None
 1.43A 3okxA-2g29A:
undetectable		 3okxA-2g29A:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 8 PHE A 427
THR A 420
GLY A 417
SER A 362
 None
 1.10A 3tzfB-2g29A:
undetectable		 3tzfB-2g29A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 4 ALA A 275
VAL A 278
ASP A 279
LEU A 395
 None
 0.93A 4e7gA-2g29A:
0.3		 4e7gA-2g29A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 12 LEU A  71
THR A 190
ASP A  73
LEU A 124
GLY A 194
 NO3  A 700 (-3.7A)
NO3  A 700 (-3.9A)
NO3  A 700 ( 4.4A)
None
None
 1.39A 4pfjA-2g29A:
undetectable		 4pfjA-2g29A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		3 / 3 CYH A 309
PRO A 321
ASP A 327
 None
 0.87A 4pm5A-2g29A:
undetectable		 4pm5A-2g29A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB203_1
(CALMODULIN)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 7 PHE A 271
LEU A 147
MET A 273
ALA A 399
 None
 0.88A 4rjdB-2g29A:
undetectable		 4rjdB-2g29A:
9.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		3 / 5 GLY A 156
GLY A 154
GLU A 268
 None
 0.51A 4z2eA-2g29A:
undetectable
4z2eD-2g29A:
undetectable		 4z2eA-2g29A:
24.19
4z2eD-2g29A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 12 LEU A 257
PRO A 244
GLY A 154
GLY A 240
HIS A 266
 None
None
None
NO3  A 700 (-3.2A)
None
 1.22A 5nnaA-2g29A:
undetectable		 5nnaA-2g29A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 12 LEU A 257
PRO A 244
GLY A 154
GLY A 240
HIS A 266
 None
None
None
NO3  A 700 (-3.2A)
None
 1.21A 5nnaB-2g29A:
undetectable		 5nnaB-2g29A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 12 LEU A 257
PRO A 244
GLY A 154
GLY A 240
HIS A 266
 None
None
None
NO3  A 700 (-3.2A)
None
 1.21A 5nnaC-2g29A:
undetectable		 5nnaC-2g29A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		5 / 12 LEU A 257
PRO A 244
GLY A 154
GLY A 240
HIS A 266
 None
None
None
NO3  A 700 (-3.2A)
None
 1.19A 5nnaD-2g29A:
undetectable		 5nnaD-2g29A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA304_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 4 ARG A 201
THR A 217
GLY A 212
PHE A 215
 None
 1.37A 5uunA-2g29A:
0.8		 5uunA-2g29A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_2
(-)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 4 GLN A 246
THR A 247
THR A 190
HIS A 196
 None
None
NO3  A 700 (-3.9A)
NO3  A 700 (-3.6A)
 1.50A 6f3nC-2g29A:
1.0		 6f3nC-2g29A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_2
(-)		 2g29 NITRATE TRANSPORT
PROTEIN NRTA
(Synechocystis
sp.) 		4 / 4 GLN A 246
THR A 247
THR A 190
HIS A 196
 None
None
NO3  A 700 (-3.9A)
NO3  A 700 (-3.6A)
 1.50A 6f3nD-2g29A:
0.7		 6f3nD-2g29A:
23.06