SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OK6_D_BEZD2002_0 (AROMATIC AMINE DEHYDROGENASE, LARGE SUBUNIT AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT)	2g2b	ALLOGRAFT INFLAMMATORY FACTOR 1 (Homo sapiens)	5 / 9	PHE A 53 LEU A 110 PHE A 34 GLN A 33 LEU A 27	None	1.34A	2ok6B-2g2bA: undetectable 2ok6D-2g2bA: undetectable	2ok6B-2g2bA: 19.66 2ok6D-2g2bA: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OK6_H_BEZH2001_0 (AROMATIC AMINE DEHYDROGENASE, LARGE SUBUNIT AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT)	2g2b	ALLOGRAFT INFLAMMATORY FACTOR 1 (Homo sapiens)	5 / 10	PHE A 53 LEU A 110 PHE A 34 GLN A 33 LEU A 27	None	1.33A	2ok6A-2g2bA: undetectable 2ok6H-2g2bA: undetectable	2ok6A-2g2bA: 19.66 2ok6H-2g2bA: 15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6H_A_CXXA802_1 (TRANSPORTER)	2g2b	ALLOGRAFT INFLAMMATORY FACTOR 1 (Homo sapiens)	4 / 7	ILE A 68 ARG A 26 ILE A 30 PHE A 53	None	0.99A	2q6hA-2g2bA: undetectable	2q6hA-2g2bA: 14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_G_CHDG103_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	2g2b	ALLOGRAFT INFLAMMATORY FACTOR 1 (Homo sapiens)	6 / 11	LEU A 46 TYR A 40 GLU A 51 LEU A 110 ARG A 111 LEU A 114	None	1.49A	4wg0E-2g2bA: undetectable 4wg0F-2g2bA: undetectable 4wg0G-2g2bA: undetectable	4wg0E-2g2bA: 8.26 4wg0F-2g2bA: 8.26 4wg0G-2g2bA: 8.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OK6_D_BEZD2002_0","AROMATIC AMINE DEHYDROGENASE, LARGE SUBUNIT;AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT","2g2b","ALLOGRAFT INFLAMMATORY FACTOR 1","Homo sapiens",5,"PHE A  53;LEU A 110;PHE A  34;GLN A  33;LEU A  27","None","1.34A","2ok6B-2g2bA:undetectable;2ok6D-2g2bA:undetectable","2ok6B-2g2bA:19.66;2ok6D-2g2bA:15.33"],["2OK6_H_BEZH2001_0","AROMATIC AMINE DEHYDROGENASE, LARGE SUBUNIT;AROMATIC AMINE DEHYDROGENASE, SMALL SUBUNIT","2g2b","ALLOGRAFT INFLAMMATORY FACTOR 1","Homo sapiens",5,"PHE A  53;LEU A 110;PHE A  34;GLN A  33;LEU A  27","None","1.33A","2ok6A-2g2bA:undetectable;2ok6H-2g2bA:undetectable","2ok6A-2g2bA:19.66;2ok6H-2g2bA:15.33"],["2Q6H_A_CXXA802_1","TRANSPORTER","2g2b","ALLOGRAFT INFLAMMATORY FACTOR 1","Homo sapiens",4,"ILE A  68;ARG A  26;ILE A  30;PHE A  53","None","0.99A","2q6hA-2g2bA:undetectable","2q6hA-2g2bA:14.86"],["4WG0_G_CHDG103_0","NUCLEAR RECEPTOR COACTIVATOR 2","2g2b","ALLOGRAFT INFLAMMATORY FACTOR 1","Homo sapiens",6,"LEU A  46;TYR A  40;GLU A  51;LEU A 110;ARG A 111;LEU A 114","None","1.49A","4wg0E-2g2bA:undetectable;4wg0F-2g2bA:undetectable;4wg0G-2g2bA:undetectable","4wg0E-2g2bA:8.26;4wg0F-2g2bA:8.26;4wg0G-2g2bA:8.26"]]