SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g2c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_A_SAMA1501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 THR A  84
GLU A  50
THR A  76
SER A 138
 None
None
NA  A 301 (-3.3A)
NA  A 301 (-3.6A)
 1.20A 1tv8A-2g2cA:
undetectable		 1tv8A-2g2cA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 THR A  84
GLU A  50
THR A  76
SER A 138
 None
None
NA  A 301 (-3.3A)
NA  A 301 (-3.6A)
 1.20A 1tv8B-2g2cA:
undetectable		 1tv8B-2g2cA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XF1_A_ACTA1107_0
(C5A PEPTIDASE)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 5 GLY A 125
HIS A  93
ILE A  92
PHE A  91
 None
 0.92A 1xf1A-2g2cA:
4.4		 1xf1A-2g2cA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BU8_A_TF4A1379_1
(PYRUVATE
DEHYDROGENASE KINASE
ISOENZYME 2)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 8 LEU A  99
ILE A 157
ILE A 150
ILE A 154
 None
 0.83A 2bu8A-2g2cA:
undetectable		 2bu8A-2g2cA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 PHE A  69
ILE A   3
THR A  72
GLY A 122
 None
 0.88A 2v0mB-2g2cA:
undetectable		 2v0mB-2g2cA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 7 THR A  76
GLY A 119
THR A  84
VAL A 121
 NA  A 301 (-3.3A)
None
None
None
 0.97A 4qwpB-2g2cA:
undetectable		 4qwpB-2g2cA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 4 LEU A 132
ILE A  70
GLY A 122
ILE A  59
 None
 0.87A 5dzk3-2g2cA:
undetectable
5dzkm-2g2cA:
undetectable		 5dzk3-2g2cA:
6.67
5dzkm-2g2cA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 5 ILE A  70
GLY A 122
ILE A  59
LEU A 132
 None
 0.82A 5dzkB-2g2cA:
2.3
5dzkI-2g2cA:
undetectable
5dzkW-2g2cA:
undetectable		 5dzkB-2g2cA:
23.32
5dzkI-2g2cA:
24.39
5dzkW-2g2cA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2g2c PUTATIVE MOLYBDENUM
COFACTOR
BIOSYNTHESIS PROTEIN
(Corynebacterium
diphtheriae) 		4 / 5 ILE A  70
GLY A 122
ILE A  59
LEU A 132
 None
 0.83A 5dzki-2g2cA:
undetectable
5dzkj-2g2cA:
undetectable
5dzkx-2g2cA:
undetectable		 5dzki-2g2cA:
24.39
5dzkj-2g2cA:
24.39
5dzkx-2g2cA:
6.67