SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g2p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 2g2p TRANSTHYRETIN-LIKE
PROTEIN
(Escherichia
coli) 		4 / 6 LEU A   6
ILE A  84
TYR A 111
VAL A  24
 None
None
SO4  A1102 (-4.2A)
None
 1.09A 1db1A-2g2pA:
undetectable		 1db1A-2g2pA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2g2p TRANSTHYRETIN-LIKE
PROTEIN
(Escherichia
coli) 		4 / 8 THR A  68
THR A 110
VAL A   8
VAL A  99
 None
 0.79A 1t86A-2g2pA:
undetectable		 1t86A-2g2pA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 2g2p TRANSTHYRETIN-LIKE
PROTEIN
(Escherichia
coli) 		4 / 5 ASP A  43
SER A   7
VAL A   8
GLY A  46
 None
ZN  A1005 ( 4.1A)
None
None
 1.10A 3rxhA-2g2pA:
undetectable		 3rxhA-2g2pA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 2g2p TRANSTHYRETIN-LIKE
PROTEIN
(Escherichia
coli) 		4 / 5 LEU A  37
TYR A  62
ALA A  57
ILE A   5
 None
 1.05A 4y03B-2g2pA:
undetectable		 4y03B-2g2pA:
21.48