SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g2r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2g2r GREEN-FLUORESCENT
ANTIBODY
(11G10)-HEAVY CHAIN
(Mus
musculus) 		4 / 6 ASP H  96
TYR H  95
PHE H  29
TYR H  27
 None
 1.10A 2w98A-2g2rH:
undetectable
2w98B-2g2rH:
undetectable		 2w98A-2g2rH:
19.70
2w98B-2g2rH:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2g2r GREEN-FLUORESCENT
ANTIBODY
(11G10)-HEAVY CHAIN
(Mus
musculus) 		4 / 8 VAL H  50
VAL H  93
TYR H  95
TYR H  33
 None
 0.99A 4pwdA-2g2rH:
undetectable		 4pwdA-2g2rH:
17.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 2g2r GREEN-FLUORESCENT
ANTIBODY
(11G10)-HEAVY CHAIN
(Mus
musculus) 		4 / 5 SER H 112
ALA H 114
PHE H 148
LEU H 178
 None
 0.30A 5mthA-2g2rH:
29.0		 5mthA-2g2rH:
73.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 2g2r GREEN-FLUORESCENT
ANTIBODY
(11G10)-HEAVY CHAIN
(Mus
musculus) 		4 / 5 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 0.92A 5xdhB-2g2rH:
undetectable		 5xdhB-2g2rH:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 2g2r GREEN-FLUORESCENT
ANTIBODY
(11G10)-HEAVY CHAIN
(Mus
musculus) 		4 / 6 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 0.92A 5xdhA-2g2rH:
undetectable
5xdhC-2g2rH:
undetectable		 5xdhA-2g2rH:
16.24
5xdhC-2g2rH:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 2g2r GREEN-FLUORESCENT
ANTIBODY
(11G10)-HEAVY CHAIN
(Mus
musculus) 		4 / 5 MET H  80
ASN H  76
VAL H  71
LEU H  69
 None
 0.92A 5xdhD-2g2rH:
undetectable		 5xdhD-2g2rH:
16.24