SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g2x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 2g2x HYPOTHETICAL PROTEIN
PP5205
(Pseudomonas
putida) 		3 / 4 VAL A  99
TRP A   4
TRP A  26
 None
None
SO4  A 301 (-3.4A)
 1.19A 1gmkC-2g2xA:
undetectable
1gmkD-2g2xA:
undetectable		 1gmkC-2g2xA:
8.04
1gmkD-2g2xA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 2g2x HYPOTHETICAL PROTEIN
PP5205
(Pseudomonas
putida) 		5 / 12 THR A  74
SER A  80
GLY A  22
LEU A  21
LEU A  18
 None
 1.05A 2hw2A-2g2xA:
undetectable		 2hw2A-2g2xA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 2g2x HYPOTHETICAL PROTEIN
PP5205
(Pseudomonas
putida) 		4 / 8 ALA A 100
PHE A  47
ILE A  65
THR A  66
 None
 0.96A 3bpxA-2g2xA:
undetectable
3bpxB-2g2xA:
undetectable		 3bpxA-2g2xA:
22.02
3bpxB-2g2xA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2g2x HYPOTHETICAL PROTEIN
PP5205
(Pseudomonas
putida) 		5 / 11 ILE A  15
ALA A  19
ARG A  64
ALA A 100
VAL A 108
 None
 0.80A 4nqaA-2g2xA:
undetectable		 4nqaA-2g2xA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 2g2x HYPOTHETICAL PROTEIN
PP5205
(Pseudomonas
putida) 		5 / 11 GLU A 110
ARG A 107
GLY A  61
ALA A  60
ILE A 145
 None
 1.07A 5yk2A-2g2xA:
undetectable		 5yk2A-2g2xA:
16.96