SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g3b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHI_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 11 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 1dhiB-2g3bA:
undetectable
1dhiB-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.01A 1dhjB-2g3bA:
undetectable
1dhjB-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.99A 1draA-2g3bA:
undetectable
1draA-2g3bA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 1draB-2g3bA:
undetectable
1draB-2g3bA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.01A 1drbB-2g3bA:
undetectable
1drbB-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 11 ALA A  53
VAL A  26
ALA A  30
ALA A  33
LEU A   9
None
1.06A 1jinA-2g3bA:
2.0
1jinA-2g3bA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7F_A_BCZA801_0
(NEURAMINIDASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 GLU A 160
ARG A 105
ILE A  58
GLU A  87
ARG A  66
None
None
None
GOL  A1004 (-2.7A)
GOL  A1004 (-3.1A)
1.47A 1l7fA-2g3bA:
undetectable
1l7fA-2g3bA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
4 / 8 GLY A  23
ILE A  21
SER A 107
GLU A 111
None
0.87A 1mrjA-2g3bA:
undetectable
1mrjA-2g3bA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 9 LEU A 146
ALA A 152
THR A 156
LEU A  84
LEU A  80
None
1.00A 1nr6A-2g3bA:
undetectable
1nr6A-2g3bA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 1ra2A-2g3bA:
undetectable
1ra2A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.02A 1ra3A-2g3bA:
undetectable
1ra3A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 1ra8A-2g3bA:
undetectable
1ra8A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.96A 1rb2A-2g3bA:
undetectable
1rb2A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 10 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.96A 1rb3A-2g3bA:
undetectable
1rb3A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB3_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.99A 1rb3B-2g3bA:
undetectable
1rb3B-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 1rd7A-2g3bA:
undetectable
1rd7A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RD7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.99A 1rd7B-2g3bA:
undetectable
1rd7B-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.05A 1re7A-2g3bA:
undetectable
1re7A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.90A 1re7B-2g3bA:
undetectable
1re7B-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX2_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.01A 1rx2A-2g3bA:
undetectable
1rx2A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.00A 2drcA-2g3bA:
undetectable
2drcA-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRC_B_MTXB161_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.00A 2drcB-2g3bA:
undetectable
2drcB-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
4 / 5 SER A 107
LEU A  24
GLY A  20
ARG A  47
None
1.15A 2j2pA-2g3bA:
undetectable
2j2pB-2g3bA:
undetectable
2j2pA-2g3bA:
20.75
2j2pB-2g3bA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAU_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  58
ALA A  11
ILE A  21
ARG A  47
LEU A  51
None
1.09A 3dauA-2g3bA:
undetectable
3dauA-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.99A 3drcA-2g3bA:
undetectable
3drcA-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DRC_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 3drcB-2g3bA:
undetectable
3drcB-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.99A 3ql3A-2g3bA:
undetectable
3ql3A-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.02A 3tq9A-2g3bA:
undetectable
3tq9A-2g3bA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_B_MTXB162_1
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.00A 4dfrB-2g3bA:
undetectable
4dfrB-2g3bA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJ1_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.94A 4ej1A-2g3bA:
undetectable
4ej1A-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.95A 4fhbA-2g3bA:
undetectable
4fhbA-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.99A 4i13A-2g3bA:
undetectable
4i13A-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_0
(NEURAMINIDASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 GLU A 160
ARG A 105
ILE A  58
GLU A  87
ARG A  66
None
None
None
GOL  A1004 (-2.7A)
GOL  A1004 (-3.1A)
1.50A 4mwvA-2g3bA:
undetectable
4mwvA-2g3bA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.97A 4p3rA-2g3bA:
undetectable
4p3rA-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 4ptjA-2g3bA:
undetectable
4ptjA-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5G_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.96A 4x5gB-2g3bA:
undetectable
4x5gB-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
1.01A 4x5jA-2g3bA:
undetectable
4x5jA-2g3bA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
4 / 6 LEU A 180
LEU A  84
SER A  83
VAL A  94
None
1.22A 5a6iA-2g3bA:
undetectable
5a6iA-2g3bA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.97A 5e8qA-2g3bA:
undetectable
5e8qA-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.95A 5eajA-2g3bA:
undetectable
5eajA-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
3 / 3 ALA A  76
GLN A 137
THR A 139
None
0.66A 5n0oA-2g3bA:
undetectable
5n0oA-2g3bA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
5 / 12 ILE A  21
ALA A 106
LEU A 118
ILE A  58
ILE A  16
None
0.98A 5ujxA-2g3bA:
undetectable
5ujxA-2g3bA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii)
4 / 5 THR A 121
GLU A  52
HIS A  43
LEU A   9
None
1.13A 5utuH-2g3bA:
undetectable
5utuH-2g3bA:
18.11