SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 2g3k VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN VPS28
(Saccharomyces
cerevisiae) 		4 / 8 THR A 192
VAL A 191
ASN A 159
PHE A 196
 None
 1.17A 2ij7C-2g3kA:
undetectable		 2ij7C-2g3kA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 2g3k VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN VPS28
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 181
LEU A 230
ALA A 233
SER A 236
LEU A 184
 None
 0.90A 6b0cD-2g3kA:
undetectable		 6b0cD-2g3kA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 2g3k VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN VPS28
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 181
ALA A 233
SER A 236
PHE A 160
LEU A 184
 None
 1.21A 6ew0G-2g3kA:
undetectable		 6ew0G-2g3kA:
21.65