SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_A_SALA3002_1 (TRANSCRIPTIONAL REGULATOR TCAR)	2g3y	GTP-BINDING PROTEIN GEM (Homo sapiens)	5 / 8	LEU A 91 LEU A 231 ILE A 127 VAL A 78 LEU A 154	None	1.38A	3kp6A-2g3yA: undetectable 3kp6B-2g3yA: undetectable	3kp6A-2g3yA: 21.43 3kp6B-2g3yA: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX7_A_H4BA600_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	2g3y	GTP-BINDING PROTEIN GEM (Homo sapiens)	4 / 8	SER A 193 ARG A 207 ILE A 159 PHE A 217	None	1.25A	4cx7A-2g3yA: undetectable 4cx7B-2g3yA: undetectable	4cx7A-2g3yA: 18.78 4cx7B-2g3yA: 18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX7_C_H4BC600_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	2g3y	GTP-BINDING PROTEIN GEM (Homo sapiens)	4 / 8	SER A 193 ARG A 207 ILE A 159 PHE A 217	None	1.21A	4cx7C-2g3yA: undetectable 4cx7D-2g3yA: undetectable	4cx7C-2g3yA: 18.78 4cx7D-2g3yA: 18.78