SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g4r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.88A 1muiA-2g4rA:
undetectable		 1muiA-2g4rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.91A 1rl8A-2g4rA:
undetectable		 1rl8A-2g4rA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.86A 1sdvB-2g4rA:
undetectable		 1sdvB-2g4rA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.82A 2f81A-2g4rA:
undetectable		 2f81A-2g4rA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.86A 2hs2B-2g4rA:
undetectable		 2hs2B-2g4rA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.79A 2ienA-2g4rA:
undetectable		 2ienA-2g4rA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.82A 2ienB-2g4rA:
undetectable		 2ienB-2g4rA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.86A 2o4sA-2g4rA:
undetectable		 2o4sA-2g4rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.87A 2r5pD-2g4rA:
undetectable		 2r5pD-2g4rA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.85A 2rkfB-2g4rA:
undetectable		 2rkfB-2g4rA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.85A 2rkgA-2g4rA:
undetectable		 2rkgA-2g4rA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 ILE A  67
LEU A 128
ILE A  28
ILE A  99
VAL A 145
 None
 1.15A 2ygnA-2g4rA:
undetectable		 2ygnA-2g4rA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.93A 2z54B-2g4rA:
undetectable		 2z54B-2g4rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.81A 3d20A-2g4rA:
undetectable		 3d20A-2g4rA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.87A 3ekpD-2g4rA:
undetectable		 3ekpD-2g4rA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.85A 3ektC-2g4rA:
undetectable		 3ektC-2g4rA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.83A 3ektD-2g4rA:
undetectable		 3ektD-2g4rA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 ILE A  67
ALA A   6
LEU A  32
ILE A  99
CYH A 117
 None
 0.99A 3fc6A-2g4rA:
undetectable		 3fc6A-2g4rA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 THR A  68
LEU A  55
VAL A  63
GLY A  62
ILE A 153
 None
 0.85A 3ijdA-2g4rA:
undetectable		 3ijdA-2g4rA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.87A 3lzsB-2g4rA:
undetectable		 3lzsB-2g4rA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.85A 3lzuA-2g4rA:
undetectable		 3lzuA-2g4rA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.81A 3lzuB-2g4rA:
undetectable		 3lzuB-2g4rA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.85A 3mwsA-2g4rA:
undetectable		 3mwsA-2g4rA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.82A 3pwmA-2g4rA:
undetectable		 3pwmA-2g4rA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.83A 3s54A-2g4rA:
undetectable		 3s54A-2g4rA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.88A 3tkwB-2g4rA:
undetectable		 3tkwB-2g4rA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.79A 3ttpA-2g4rA:
undetectable		 3ttpA-2g4rA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.80A 3ttpB-2g4rA:
undetectable		 3ttpB-2g4rA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V1N_A_BEZA288_0
(2-HYDROXY-6-OXO-6-PH
ENYLHEXA-2,4-DIENOAT
E HYDROLASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 8 GLY A  70
GLY A 130
SER A  69
ILE A  27
LEU A 139
 CL  A 201 (-3.3A)
CL  A 201 (-3.9A)
None
None
None
 1.31A 3v1nA-2g4rA:
3.4		 3v1nA-2g4rA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  32
ILE A  99
ILE A 126
VAL A  65
LEU A 124
 None
 0.98A 3w67D-2g4rA:
undetectable		 3w67D-2g4rA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  32
ILE A  99
ILE A 126
VAL A  65
LEU A 124
 None
 0.97A 3w68C-2g4rA:
undetectable		 3w68C-2g4rA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 LEU A  32
ILE A  99
ILE A 126
VAL A  65
LEU A 124
 None
 1.04A 3w68D-2g4rA:
undetectable		 3w68D-2g4rA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  47
VAL A  11
GLY A  70
ASP A  78
 None
None
CL  A 201 (-3.3A)
None
 1.45A 3w9tB-2g4rA:
undetectable		 3w9tB-2g4rA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  47
VAL A  11
GLY A  70
ASP A  78
 None
None
CL  A 201 (-3.3A)
None
 1.45A 3w9tC-2g4rA:
undetectable		 3w9tC-2g4rA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 ASP A  47
VAL A  11
GLY A  70
ASP A  78
 None
None
CL  A 201 (-3.3A)
None
 1.44A 3w9tG-2g4rA:
undetectable		 3w9tG-2g4rA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.81A 4hlaB-2g4rA:
undetectable		 4hlaB-2g4rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.88A 4ll3B-2g4rA:
undetectable		 4ll3B-2g4rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.86A 4ll3A-2g4rA:
undetectable		 4ll3A-2g4rA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 7 ARG A   4
PHE A  37
LEU A 146
ASP A 147
 None
 1.02A 4mmcA-2g4rA:
undetectable		 4mmcA-2g4rA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_2
(ADENOSINE KINASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 CYH A  24
LEU A 128
SER A 131
LEU A 139
 None
 1.32A 4n09D-2g4rA:
undetectable		 4n09D-2g4rA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.85A 4njvB-2g4rA:
undetectable		 4njvB-2g4rA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ILE A  28
ASP A  22
ARG A 136
 None
 0.83A 4pstA-2g4rA:
undetectable		 4pstA-2g4rA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.78A 5e5jB-2g4rA:
undetectable		 5e5jB-2g4rA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 2g4r MOLYBDOPTERIN
BIOSYNTHESIS MOG
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 115
ASP A  97
GLY A 118
ILE A 125
ILE A  99
 None
TRS  A 301 (-2.8A)
None
None
None
 0.76A 5t8hB-2g4rA:
undetectable		 5t8hB-2g4rA:
21.12