SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g5g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_D_DESD128_1
(TRANSTHYRETIN)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 4 LYS X 189
LEU X 186
LEU X 178
SER X 173
 None
HEM  X 605 (-4.3A)
HEM  X 605 ( 4.9A)
None
 1.47A 1tz8D-2g5gX:
undetectable		 1tz8D-2g5gX:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 ILE X 147
ARG X 200
LEU X 139
GLU X 143
 None
 1.01A 2cdqA-2g5gX:
undetectable		 2cdqA-2g5gX:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 GLU X  80
TYR X 219
HIS X 220
GLY X 217
 None
 0.88A 2ha4A-2g5gX:
undetectable		 2ha4A-2g5gX:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 TYR X 120
GLU X  80
HIS X 220
GLY X 217
 None
 1.06A 2ha4A-2g5gX:
undetectable		 2ha4A-2g5gX:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 7 GLU X  80
TYR X 219
HIS X 220
GLY X 217
 None
 0.87A 2ha4B-2g5gX:
undetectable		 2ha4B-2g5gX:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 7 TYR X 120
GLU X  80
HIS X 220
GLY X 217
 None
 1.08A 2ha4B-2g5gX:
undetectable		 2ha4B-2g5gX:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 GLU X  80
HIS X 220
TYR X 219
HIS X  48
 None
 0.91A 3a6jA-2g5gX:
undetectable		 3a6jA-2g5gX:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 7 GLU X  80
HIS X 220
TYR X 219
HIS X  48
 None
 0.92A 3a6jB-2g5gX:
undetectable		 3a6jB-2g5gX:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 GLU X  80
HIS X 220
TYR X 219
HIS X  48
 None
 0.89A 3a6jC-2g5gX:
undetectable		 3a6jC-2g5gX:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 GLU X  80
HIS X 220
TYR X 219
HIS X  48
 None
 0.93A 3a6jE-2g5gX:
undetectable		 3a6jE-2g5gX:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 GLU X  80
HIS X 220
TYR X 219
HIS X  48
 None
 0.90A 3a6jF-2g5gX:
undetectable		 3a6jF-2g5gX:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 SER X  70
GLN X  71
ILE X  42
VAL X 241
 None
 0.95A 4dx7B-2g5gX:
undetectable		 4dx7B-2g5gX:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_C_PARC500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		5 / 10 SER X 255
THR X 221
GLU X  80
ASP X 198
GLY X  45
 None
 1.49A 4qb9C-2g5gX:
0.0		 4qb9C-2g5gX:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 LEU X  44
VAL X 243
ILE X  33
LEU X  64
 None
 0.63A 4qrcA-2g5gX:
undetectable		 4qrcA-2g5gX:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		5 / 9 THR X 221
ILE X 240
LEU X 215
LEU X  36
ILE X  60
 None
 1.31A 4r38C-2g5gX:
undetectable		 4r38C-2g5gX:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		5 / 8 THR X 221
ILE X 240
LEU X 215
LEU X  36
ILE X  60
 None
 1.31A 4r38D-2g5gX:
undetectable		 4r38D-2g5gX:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		5 / 11 ALA X 137
ALA X  78
VAL X 212
LEU X 214
VAL X  41
 None
 0.97A 5eb5A-2g5gX:
undetectable		 5eb5A-2g5gX:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 8 ASN X  62
GLN X  57
PHE X  61
ASN X 125
 None
 1.25A 5vunA-2g5gX:
undetectable		 5vunA-2g5gX:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2g5g PUTATIVE LIPOPROTEIN
(Campylobacter
jejuni) 		4 / 6 LEU X  79
VAL X  77
LEU X 213
VAL X 127
 None
 0.94A 5x7zA-2g5gX:
undetectable		 5x7zA-2g5gX:
20.90