SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g6t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 8 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.84A 1os6A-2g6tA:
undetectable		 1os6A-2g6tA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 7 CYH A 289
SER A 288
PHE A 243
LEU A 107
 None
 1.04A 1qcaA-2g6tA:
undetectable		 1qcaA-2g6tA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		5 / 12 ILE A 112
GLY A 129
ILE A 108
VAL A 124
PHE A 216
 None
 1.16A 1sg9A-2g6tA:
2.5		 1sg9A-2g6tA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 6 LEU A  20
TYR A  13
ILE A  64
ILE A  31
 None
 0.90A 2q8hA-2g6tA:
undetectable		 2q8hA-2g6tA:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 6 ARG A 209
ILE A 108
GLU A  85
TYR A  71
 None
 1.33A 2ya7C-2g6tA:
undetectable		 2ya7C-2g6tA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K8M_A_ACRA720_1
(ALPHA-AMYLASE, SUSG)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 7 GLU A  85
LEU A  81
TRP A   7
LYS A  52
 None
 1.09A 3k8mA-2g6tA:
undetectable		 3k8mA-2g6tA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		5 / 12 ASP A 233
VAL A 253
SER A 252
HIS A 244
TYR A 250
 None
 1.31A 3mbhB-2g6tA:
3.1		 3mbhB-2g6tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		5 / 12 ASP A 233
VAL A 253
SER A 252
HIS A 244
TYR A 250
 None
 1.33A 3mbhC-2g6tA:
3.6		 3mbhC-2g6tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		5 / 12 ASP A 233
VAL A 253
SER A 252
HIS A 244
TYR A 250
 None
 1.35A 3mbhD-2g6tA:
3.6		 3mbhD-2g6tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		5 / 12 ASP A 233
VAL A 253
SER A 252
HIS A 244
TYR A 250
 None
 1.34A 3mbhE-2g6tA:
3.4		 3mbhE-2g6tA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 8 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.78A 3selX-2g6tA:
undetectable		 3selX-2g6tA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 8 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.82A 4hb6A-2g6tA:
undetectable		 4hb6A-2g6tA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 8 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.80A 4hb8A-2g6tA:
undetectable		 4hb8A-2g6tA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 7 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.84A 4hbfA-2g6tA:
undetectable		 4hbfA-2g6tA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		4 / 7 ILE A  31
LEU A  20
PHE A  66
GLY A  91
 None
 0.83A 4hc3A-2g6tA:
undetectable		 4hc3A-2g6tA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		3 / 3 LYS A  87
ILE A  63
ILE A  35
 None
 0.70A 4y0qA-2g6tA:
undetectable		 4y0qA-2g6tA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		3 / 3 TRP A   7
GLU A  77
ASP A  51
 None
 1.02A 5gqbA-2g6tA:
undetectable		 5gqbA-2g6tA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 2g6t UNCHARACTERIZED
PROTEIN, HOMOLOG
HI1244 FROM
HAEMOPHILUS
INFLUENZAE
(Clostridium
acetobutylicum) 		5 / 12 PHE A  99
PHE A  95
GLY A  91
PHE A  66
ILE A 108
 None
 1.35A 6dwnA-2g6tA:
undetectable		 6dwnA-2g6tA:
12.50