SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g6y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_A_SAMA1401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		5 / 11 LEU A  97
GLY A 120
GLY A  95
ILE A 127
LEU A  21
 None
 1.11A 1p91A-2g6yA:
undetectable		 1p91A-2g6yA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		3 / 3 SER A 172
GLY A 152
ARG A 195
 None
None
CR2  A  58 ( 4.9A)
 0.63A 1t9wA-2g6yA:
undetectable		 1t9wA-2g6yA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		3 / 3 THR A  41
ASP A 113
SER A 100
 None
 0.81A 2nxeA-2g6yA:
undetectable		 2nxeA-2g6yA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		3 / 3 THR A  41
ASP A 113
SER A 100
 None
 0.83A 2nxeB-2g6yA:
undetectable		 2nxeB-2g6yA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		3 / 3 PHE A 121
ASN A  15
PHE A 128
 None
 0.93A 2zbuD-2g6yA:
undetectable		 2zbuD-2g6yA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		5 / 10 ILE A   6
GLY A  23
CYH A   8
ARG A   9
ILE A 111
 None
 1.22A 3adsA-2g6yA:
undetectable		 3adsA-2g6yA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		5 / 12 ILE A 132
PHE A 121
LEU A  14
SER A 168
TYR A  91
 None
 1.46A 3apwB-2g6yA:
undetectable		 3apwB-2g6yA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		4 / 8 ALA A 179
ILE A 180
ASN A 148
PRO A 144
 None
 0.83A 3fxrA-2g6yA:
undetectable		 3fxrA-2g6yA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		3 / 3 ILE A 180
PHE A  74
HIS A 143
 None
 0.55A 3h0aA-2g6yA:
undetectable		 3h0aA-2g6yA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		5 / 12 VAL A  55
LEU A  52
SER A  48
PHE A  47
GLY A 118
 None
 1.13A 3kk6B-2g6yA:
undetectable		 3kk6B-2g6yA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		4 / 6 PHE A  47
HIS A  98
VAL A 170
PHE A 121
 None
 1.04A 4a97E-2g6yA:
undetectable		 4a97E-2g6yA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K87_A_ADNA602_1
(PROLINE--TRNA LIGASE)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		4 / 8 ARG A  87
PHE A 154
GLN A 212
THR A 138
 CR2  A  58 ( 3.5A)
CR2  A  58 ( 4.3A)
None
CR2  A  58 ( 2.7A)
 0.94A 4k87A-2g6yA:
undetectable		 4k87A-2g6yA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		4 / 4 LEU A  45
SER A  48
LEU A  14
LEU A  21
 None
 1.06A 4n09A-2g6yA:
undetectable		 4n09A-2g6yA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		4 / 8 ASN A  85
PHE A 101
PHE A  74
TYR A 105
 None
CR2  A  58 ( 4.3A)
None
None
 1.47A 4v2zC-2g6yA:
undetectable		 4v2zC-2g6yA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		5 / 10 VAL A 110
TYR A 105
TYR A 103
GLY A  64
PHE A  63
 None
None
CR2  A  58 ( 4.5A)
None
None
 1.46A 4xpbA-2g6yA:
undetectable		 4xpbA-2g6yA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_2
(-)		 2g6y GREEN FLUORESCENT
PROTEIN 2
(Pontellina
plumata) 		4 / 6 HIS A 173
ASN A  85
TYR A  83
GLU A 140
 None
 1.45A 6gneA-2g6yA:
undetectable		 6gneA-2g6yA:
17.19