SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g7e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A28_A_STRA1_1 (PROGESTERONE RECEPTOR)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	5 / 12	LEU A 119 ASN A 118 LEU A 116 GLN A 217 MET A 177	None	1.32A	1a28A-2g7eA: 0.0	1a28A-2g7eA: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A28_B_STRB2_1 (PROGESTERONE RECEPTOR)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	5 / 12	LEU A 119 ASN A 118 LEU A 116 GLN A 217 MET A 177	None	1.28A	1a28B-2g7eA: undetectable	1a28B-2g7eA: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DMI_A_BHSA1610_1 (NITRIC OXIDE SYNTHASE)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	4 / 8	VAL A 81 ARG A 209 ALA A 166 GLU A 79	None	1.08A	1dmiA-2g7eA: undetectable 1dmiB-2g7eA: undetectable	1dmiA-2g7eA: 18.84 1dmiB-2g7eA: 18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SQN_A_NDRA1001_0 (PROGESTERONE RECEPTOR)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	5 / 12	LEU A 119 ASN A 118 LEU A 116 GLN A 217 MET A 177	None	1.35A	1sqnA-2g7eA: undetectable	1sqnA-2g7eA: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2COJ_B_GBNB420_1 (BRANCHED CHAIN AMINOTRANSFERASE 1, CYTOSOLIC)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	5 / 9	TYR A 43 ARG A 130 THR A 173 GLY A 168 ALA A 166	None	1.42A	2cojA-2g7eA: undetectable 2cojB-2g7eA: undetectable	2cojA-2g7eA: 19.42 2cojB-2g7eA: 19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA509_0 (CHORISMATE SYNTHASE)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	3 / 3	ARG A 130 GLN A 86 PRO A 83	None	0.61A	2qhfA-2g7eA: undetectable	2qhfA-2g7eA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_E_DVAE7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	3 / 3	TYR A 35 SER A 41 TRP A 78	None CL A 300 (-3.1A) None	0.74A	5n8jB-2g7eA: undetectable	5n8jB-2g7eA: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_O_DVAO7_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	3 / 3	TYR A 35 SER A 41 TRP A 78	None CL A 300 (-3.1A) None	0.70A	5n8jA-2g7eA: undetectable	5n8jA-2g7eA: 18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N8J_P_DVAP5_0 (GLY-DTY-GLY-DLE-DAL- DSG-DVA-DAS-DGL-DSN- DSN-GLY STREPTAVIDIN)	2g7e	ENDONUCLEASE I (Vibrio cholerae)	3 / 3	TYR A 35 SER A 41 TRP A 78	None CL A 300 (-3.1A) None	0.68A	5n8jD-2g7eA: undetectable	5n8jD-2g7eA: 18.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A28_A_STRA1_1","PROGESTERONE RECEPTOR","2g7e","ENDONUCLEASE I","Vibrio cholerae",5,"LEU A 119;ASN A 118;LEU A 116;GLN A 217;MET A 177","None","1.32A","1a28A-2g7eA:0.0","1a28A-2g7eA:19.19"],["1A28_B_STRB2_1","PROGESTERONE RECEPTOR","2g7e","ENDONUCLEASE I","Vibrio cholerae",5,"LEU A 119;ASN A 118;LEU A 116;GLN A 217;MET A 177","None","1.28A","1a28B-2g7eA:undetectable","1a28B-2g7eA:19.19"],["1DMI_A_BHSA1610_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","2g7e","ENDONUCLEASE I","Vibrio cholerae",4,"VAL A  81;ARG A 209;ALA A 166;GLU A  79","None","1.08A","1dmiA-2g7eA:undetectable;1dmiB-2g7eA:undetectable","1dmiA-2g7eA:18.84;1dmiB-2g7eA:18.84"],["1SQN_A_NDRA1001_0","PROGESTERONE RECEPTOR","2g7e","ENDONUCLEASE I","Vibrio cholerae",5,"LEU A 119;ASN A 118;LEU A 116;GLN A 217;MET A 177","None","1.35A","1sqnA-2g7eA:undetectable","1sqnA-2g7eA:19.20"],["2COJ_B_GBNB420_1","BRANCHED CHAIN AMINOTRANSFERASE 1, CYTOSOLIC;BRANCHED CHAIN AMINOTRANSFERASE 1, CYTOSOLIC","2g7e","ENDONUCLEASE I","Vibrio cholerae",5,"TYR A  43;ARG A 130;THR A 173;GLY A 168;ALA A 166","None","1.42A","2cojA-2g7eA:undetectable;2cojB-2g7eA:undetectable","2cojA-2g7eA:19.42;2cojB-2g7eA:19.42"],["2QHF_A_ACTA509_0","CHORISMATE SYNTHASE","2g7e","ENDONUCLEASE I","Vibrio cholerae",3,"ARG A 130;GLN A  86;PRO A  83","None","0.61A","2qhfA-2g7eA:undetectable","2qhfA-2g7eA:19.29"],["5N8J_E_DVAE7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","2g7e","ENDONUCLEASE I","Vibrio cholerae",3,"TYR A  35;SER A  41;TRP A  78","None; CL A 300 (-3.1A);None","0.74A","5n8jB-2g7eA:undetectable","5n8jB-2g7eA:18.92"],["5N8J_O_DVAO7_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","2g7e","ENDONUCLEASE I","Vibrio cholerae",3,"TYR A  35;SER A  41;TRP A  78","None; CL A 300 (-3.1A);None","0.70A","5n8jA-2g7eA:undetectable","5n8jA-2g7eA:18.92"],["5N8J_P_DVAP5_0","GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY;STREPTAVIDIN","2g7e","ENDONUCLEASE I","Vibrio cholerae",3,"TYR A  35;SER A  41;TRP A  78","None; CL A 300 (-3.1A);None","0.68A","5n8jD-2g7eA:undetectable","5n8jD-2g7eA:18.92"]]