SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g7g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 ALA A 174
ALA A 173
THR A 164
THR A 169
ARG A 170
 None
None
ACY  A 302 (-3.5A)
None
None
 1.27A 1cbrA-2g7gA:
undetectable		 1cbrA-2g7gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 ALA A 174
ALA A 173
THR A 164
THR A 169
ARG A 170
 None
None
ACY  A 302 (-3.5A)
None
None
 1.27A 1cbrB-2g7gA:
undetectable		 1cbrB-2g7gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 9 LEU A 200
LEU A 122
ALA A 134
ALA A 139
PHE A  80
 None
 1.28A 2vcvE-2g7gA:
undetectable		 2vcvE-2g7gA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 10 GLU A  65
VAL A 135
ALA A 138
PHE A 186
LEU A 190
 None
 1.25A 3a3yA-2g7gA:
undetectable		 3a3yA-2g7gA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 9 VAL A  62
LEU A 148
ILE A  98
ALA A  97
ALA A 151
 None
 1.05A 3mdvA-2g7gA:
undetectable		 3mdvA-2g7gA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 11 VAL A 106
ILE A  66
TYR A 115
TYR A  87
GLU A 140
 None
 1.27A 3q5rA-2g7gA:
0.0		 3q5rA-2g7gA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 LEU A 193
PHE A  71
ILE A 132
ILE A 136
PHE A 142
 None
 1.02A 3w67B-2g7gA:
undetectable		 3w67B-2g7gA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 LEU A 193
PHE A  71
ILE A 132
ILE A 136
PHE A 142
 None
 0.90A 3w68D-2g7gA:
undetectable		 3w68D-2g7gA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 TYR A 115
ARG A  59
SER A 111
 None
 1.06A 4dr2I-2g7gA:
undetectable
4dr2J-2g7gA:
undetectable		 4dr2I-2g7gA:
21.33
4dr2J-2g7gA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 TYR A 115
ARG A  59
SER A 111
 None
 0.72A 4khpI-2g7gA:
undetectable
4khpJ-2g7gA:
undetectable		 4khpI-2g7gA:
20.85
4khpJ-2g7gA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 TYR A 115
ARG A  59
SER A 111
 None
 1.13A 4lf7I-2g7gA:
undetectable
4lf7J-2g7gA:
undetectable		 4lf7I-2g7gA:
21.33
4lf7J-2g7gA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 TYR A 115
ARG A  59
SER A 111
 None
 1.13A 4lf8I-2g7gA:
undetectable
4lf8J-2g7gA:
undetectable		 4lf8I-2g7gA:
21.33
4lf8J-2g7gA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 ILE A 132
GLU A  72
PHE A  80
ALA A 139
SER A 113
 None
 1.14A 5igyA-2g7gA:
undetectable		 5igyA-2g7gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 ILE A 132
GLU A  72
PHE A  80
ALA A 139
SER A 113
 None
 1.25A 5ih0A-2g7gA:
undetectable		 5ih0A-2g7gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 ILE A 132
GLU A  72
PHE A  80
ALA A 139
SER A 113
 None
 1.23A 5iwuA-2g7gA:
undetectable		 5iwuA-2g7gA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 VAL A 114
LEU A 190
LEU A 143
GLY A 121
LEU A 122
 None
 1.02A 6b0iB-2g7gA:
undetectable		 6b0iB-2g7gA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0L_B_TA1B502_1
(TUBULIN BETA CHAIN)		 2g7g RHA04620, PUTATIVE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 VAL A 114
LEU A 190
LEU A 143
GLY A 121
LEU A 122
 None
 0.95A 6b0lB-2g7gA:
undetectable		 6b0lB-2g7gA:
15.17