SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2g7h METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Methanocaldococc
us
jannaschii) 		3 / 3 TYR A 140
LEU A 122
ARG A 119
 None
 0.72A 3sufB-2g7hA:
undetectable		 3sufB-2g7hA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2g7h METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Methanocaldococc
us
jannaschii) 		4 / 8 ALA A 116
ASP A 101
ILE A 102
ILE A  91
 None
 0.81A 4kttB-2g7hA:
undetectable		 4kttB-2g7hA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2g7h METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Methanocaldococc
us
jannaschii) 		4 / 8 ALA A 116
ASP A 101
ILE A 102
ILE A  91
 None
 0.85A 4kttD-2g7hA:
undetectable		 4kttD-2g7hA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2g7h METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Methanocaldococc
us
jannaschii) 		4 / 8 ALA A 116
ASP A 101
ILE A 102
ILE A  91
 None
 0.77A 4ndnB-2g7hA:
undetectable		 4ndnB-2g7hA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2g7h METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Methanocaldococc
us
jannaschii) 		4 / 7 ALA A 116
ASP A 101
ILE A 102
ILE A  91
 None
 0.79A 6fbnA-2g7hA:
undetectable		 6fbnA-2g7hA:
20.55