SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g7i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2g7i COMPLEMENT FACTOR H
(Homo
sapiens) 		5 / 12 ILE A1120
ASP A1119
VAL A1134
ILE A1150
PRO A1112
 None
 1.28A 2yzqA-2g7iA:
undetectable		 2yzqA-2g7iA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 2g7i COMPLEMENT FACTOR H
(Homo
sapiens) 		5 / 12 ILE A1120
THR A1121
VAL A1134
ILE A1150
PRO A1112
 None
 1.29A 2yzqA-2g7iA:
undetectable		 2yzqA-2g7iA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA702_1
(CARBONIC ANHYDRASE 2)		 2g7i COMPLEMENT FACTOR H
(Homo
sapiens) 		4 / 7 VAL A1134
TYR A1136
GLU A1159
PRO A1160
 None
 1.26A 3hs4A-2g7iA:
undetectable		 3hs4A-2g7iA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_A_SAMA1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2g7i COMPLEMENT FACTOR H
(Homo
sapiens) 		5 / 12 ILE A1120
THR A1121
VAL A1134
ILE A1150
PRO A1112
 None
 1.17A 3kpbA-2g7iA:
undetectable		 3kpbA-2g7iA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2g7i COMPLEMENT FACTOR H
(Homo
sapiens) 		5 / 12 ILE A1120
THR A1121
VAL A1134
ILE A1150
PRO A1112
 None
 1.18A 3kpbC-2g7iA:
undetectable		 3kpbC-2g7iA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 2g7i COMPLEMENT FACTOR H
(Homo
sapiens) 		5 / 12 ILE A1120
THR A1121
VAL A1134
ILE A1150
PRO A1112
 None
 1.18A 3kpdB-2g7iA:
undetectable		 3kpdB-2g7iA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 2g7i COMPLEMENT FACTOR H
(Homo
sapiens) 		4 / 8 ASP A1220
PRO A1166
TYR A1142
GLU A1145
 None
 1.10A 3oyaA-2g7iA:
undetectable		 3oyaA-2g7iA:
14.11