SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)
2g7s TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Agrobacterium
fabrum)
5 / 10 PHE A  27
ALA A  15
ARG A  16
LEU A  12
LEU A  53
None
1.17A 2bxqA-2g7sA:
3.1
2bxqA-2g7sA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)
2g7s TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Agrobacterium
fabrum)
3 / 3 ALA A 156
VAL A 136
TRP A 132
None
0.84A 3l8lC-2g7sA:
undetectable
3l8lD-2g7sA:
undetectable
3l8lC-2g7sA:
10.43
3l8lD-2g7sA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)
2g7s TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY

(Agrobacterium
fabrum)
5 / 11 ILE A  19
GLY A  23
LEU A  53
SER A  49
VAL A  54
None
0.92A 5twjD-2g7sA:
undetectable
5twjD-2g7sA:
22.50