SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 10 LEU A 182
ALA A 150
LEU A 108
ALA A 137
LEU A 146
 None
 1.29A 1ie4A-2g7uA:
undetectable
1ie4C-2g7uA:
undetectable		 1ie4A-2g7uA:
21.12
1ie4C-2g7uA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 GLY A 110
GLU A 161
ASP A 109
 None
 0.58A 2b25B-2g7uA:
undetectable		 2b25B-2g7uA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 PHE A 233
VAL A  95
SER A 141
ALA A 220
ILE A 127
 None
 1.38A 2qm9B-2g7uA:
undetectable		 2qm9B-2g7uA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 11 VAL A  18
LEU A  19
GLY A  15
ILE A  12
THR A  51
 None
 1.12A 3bjwB-2g7uA:
undetectable		 3bjwB-2g7uA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE503_1
(PHOSPHOLIPASE A2)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 11 VAL A  18
LEU A  19
GLY A  15
ILE A  12
THR A  51
 None
 1.19A 3bjwE-2g7uA:
undetectable		 3bjwE-2g7uA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 VAL A  18
LEU A  19
GLY A  15
ILE A  12
THR A  51
 None
 1.10A 3bjwF-2g7uA:
undetectable		 3bjwF-2g7uA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH504_3
(PHOSPHOLIPASE A2)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 11 VAL A  18
LEU A  19
GLY A  15
ILE A  12
THR A  51
 None
 1.08A 3bjwH-2g7uA:
undetectable		 3bjwH-2g7uA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 2g7u TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		4 / 6 LEU A 242
PHE A 233
THR A  99
VAL A  95
 None
 1.09A 4udaA-2g7uA:
undetectable		 4udaA-2g7uA:
21.95