SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g80'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 2g80 PROTEIN UTR4
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 184
ILE A 188
THR A 171
 None
 0.41A 1rg7A-2g80A:
undetectable		 1rg7A-2g80A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 2g80 PROTEIN UTR4
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 169
ASP A 168
GLY A 134
GLU A  27
ASP A  25
 None
None
None
None
MG  A 500 (-2.6A)
 1.40A 2pgfA-2g80A:
undetectable		 2pgfA-2g80A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 2g80 PROTEIN UTR4
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 218
VAL A 114
TYR A 115
 None
PE4  A 501 (-4.4A)
PE4  A 501 (-4.4A)
 0.68A 5zmqH-2g80A:
undetectable		 5zmqH-2g80A:
21.76