SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g8g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 TRP A 270
TYR A 272
LEU A 243
 None
 1.07A 1kxhA-2g8gA:
undetectable		 1kxhA-2g8gA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 LEU A 597
GLY A 598
MET A 603
VAL A 604
HIS A 628
 None
None
None
None
D5M  A  21 (-4.0A)
 1.47A 1z95A-2g8gA:
undetectable		 1z95A-2g8gA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 SER A 630
GLY A 634
HIS A 628
ILE A 478
MET A 523
 D5M  A  21 ( 4.3A)
None
D5M  A  21 (-4.0A)
None
None
 1.17A 2b25B-2g8gA:
undetectable		 2b25B-2g8gA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 GLN A 706
ASP A 714
SER A 708
TYR A 703
 None
 1.41A 2xz5A-2g8gA:
undetectable
2xz5C-2g8gA:
undetectable		 2xz5A-2g8gA:
17.37
2xz5C-2g8gA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 MET A 362
GLU A 350
ASN A 548
 None
 1.12A 3a27A-2g8gA:
undetectable		 3a27A-2g8gA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PHE A 646
GLY A 271
GLY A 367
PHE A 403
 None
 0.81A 3ko0M-2g8gA:
undetectable
3ko0P-2g8gA:
undetectable		 3ko0M-2g8gA:
10.10
3ko0P-2g8gA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 5 ARG A 728
LEU A 290
ILE A 616
PHE A 278
 None
 1.28A 3ln1D-2g8gA:
undetectable		 3ln1D-2g8gA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 11 SER A 441
THR A 442
ALA A 450
GLY A 451
THR A 452
 None
 1.23A 3mg0H-2g8gA:
undetectable
3mg0I-2g8gA:
undetectable		 3mg0H-2g8gA:
17.84
3mg0I-2g8gA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		3 / 3 GLY A 542
GLU A 721
THR A 720
 None
 0.48A 4kouA-2g8gA:
undetectable		 4kouA-2g8gA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 11 ALA A 450
GLY A 451
THR A 452
ALA A 453
THR A 443
 None
 0.83A 4qvyH-2g8gA:
undetectable		 4qvyH-2g8gA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 ALA A 450
GLY A 451
THR A 452
ALA A 453
THR A 443
 None
 0.83A 4qvyV-2g8gA:
undetectable
4qvyW-2g8gA:
undetectable		 4qvyV-2g8gA:
17.66
4qvyW-2g8gA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 ILE A 309
ASN A 326
ARG A 398
VAL A 331
ILE A 647
 None
 1.07A 4rvgA-2g8gA:
undetectable		 4rvgA-2g8gA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.46A 4v2yA-2g8gA:
0.0		 4v2yA-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.44A 4v2yB-2g8gA:
undetectable		 4v2yB-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_A_Y70A151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.48A 4v2zA-2g8gA:
0.0		 4v2zA-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.41A 4v2zB-2g8gA:
undetectable		 4v2zB-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.49A 4v2zC-2g8gA:
undetectable		 4v2zC-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_A_LVYA151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.48A 4v30A-2g8gA:
undetectable		 4v30A-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 8 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.33A 4v30B-2g8gA:
undetectable		 4v30B-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 LEU A 341
TYR A 343
PRO A 342
TYR A 366
 None
 1.26A 4z4gA-2g8gA:
undetectable		 4z4gA-2g8gA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.45A 5amiA-2g8gA:
undetectable		 5amiA-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.46A 5amjA-2g8gA:
0.0		 5amjA-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMJ_B_EF2B151_1
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.41A 5amjB-2g8gA:
0.0		 5amjB-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 11 SER A 441
THR A 442
ALA A 450
GLY A 451
THR A 452
 None
 1.18A 5bxnV-2g8gA:
undetectable
5bxnW-2g8gA:
undetectable		 5bxnV-2g8gA:
17.66
5bxnW-2g8gA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 PRO A 519
HIS A 415
GLY A 635
ASP A 609
LEU A 538
 None
 1.28A 5eeiA-2g8gA:
undetectable		 5eeiA-2g8gA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		5 / 12 PRO A 519
HIS A 415
GLY A 635
ASP A 609
LEU A 538
 None
 1.29A 5eeiB-2g8gA:
undetectable		 5eeiB-2g8gA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_A_EF2A202_0
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.48A 5oh1A-2g8gA:
undetectable		 5oh1A-2g8gA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.40A 5oh1B-2g8gA:
0.0		 5oh1B-2g8gA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_A_9V2A202_0
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.45A 5oh3A-2g8gA:
undetectable		 5oh3A-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH3_B_9V2B202_0
(CEREBLON ISOFORM 4)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 7 PRO A 299
PHE A 636
TRP A 617
TYR A 343
 None
 1.41A 5oh3B-2g8gA:
undetectable		 5oh3B-2g8gA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 GLN A 644
PHE A 275
LEU A 353
PHE A 361
 None
 1.12A 5z84P-2g8gA:
undetectable
5z84W-2g8gA:
undetectable		 5z84P-2g8gA:
19.09
5z84W-2g8gA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 GLN A 644
PHE A 275
LEU A 353
PHE A 361
 None
 1.03A 5z86C-2g8gA:
undetectable
5z86J-2g8gA:
undetectable		 5z86C-2g8gA:
19.09
5z86J-2g8gA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 GLN A 644
PHE A 275
LEU A 353
PHE A 361
 None
 1.06A 5z86P-2g8gA:
undetectable
5z86W-2g8gA:
undetectable		 5z86P-2g8gA:
19.09
5z86W-2g8gA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 GLN A 644
PHE A 275
LEU A 353
PHE A 361
 None
 1.09A 5zcoP-2g8gA:
undetectable
5zcoW-2g8gA:
undetectable		 5zcoP-2g8gA:
19.09
5zcoW-2g8gA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 GLN A 644
PHE A 275
LEU A 353
PHE A 361
 None
 1.06A 5zcpC-2g8gA:
undetectable
5zcpJ-2g8gA:
undetectable		 5zcpC-2g8gA:
19.09
5zcpJ-2g8gA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2g8g CAPSID
(Adeno-associated
dependoparvoviru
s
A) 		4 / 6 GLN A 644
PHE A 275
LEU A 353
PHE A 361
 None
 1.13A 5zcpP-2g8gA:
undetectable
5zcpW-2g8gA:
undetectable		 5zcpP-2g8gA:
19.09
5zcpW-2g8gA:
8.68