SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g9d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		3 / 3 GLU A 191
GLU A 186
LEU A 216
 None
 0.68A 1v8bA-2g9dA:
undetectable		 1v8bA-2g9dA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		3 / 3 GLU A 191
GLU A 186
LEU A 216
 None
 0.71A 1v8bB-2g9dA:
undetectable		 1v8bB-2g9dA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		3 / 3 ASP A 274
GLU A 291
ARG A 264
 None
 0.87A 1wopA-2g9dA:
undetectable		 1wopA-2g9dA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		3 / 3 VAL A 281
VAL A 311
ASP A 296
 None
 0.76A 2fumD-2g9dA:
undetectable		 2fumD-2g9dA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		4 / 8 VAL A  44
VAL A  87
ILE A 245
LEU A  73
 None
 0.85A 4jq1B-2g9dA:
undetectable		 4jq1B-2g9dA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		4 / 6 VAL A  44
VAL A  87
ILE A 245
LEU A  73
 None
 0.88A 4l1wB-2g9dA:
undetectable		 4l1wB-2g9dA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		3 / 3 THR A 101
ASN A 113
PHE A 203
 None
 0.72A 4pd9A-2g9dA:
undetectable		 4pd9A-2g9dA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		4 / 8 SER A 207
LEU A 137
ILE A 129
ALA A 130
 None
 0.84A 5te8B-2g9dA:
undetectable		 5te8B-2g9dA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		4 / 6 LEU A 136
LYS A  35
GLU A  43
LEU A  92
 None
 1.40A 5xooA-2g9dA:
undetectable		 5xooA-2g9dA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_1
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 2g9d SUCCINYLGLUTAMATE
DESUCCINYLASE
(Vibrio
cholerae) 		5 / 12 GLN A  38
VAL A  41
LEU A 133
ILE A 129
ALA A  96
 None
 1.40A 5xprA-2g9dA:
undetectable		 5xprA-2g9dA:
18.51