SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g9f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G72_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 12	TYR A 501 THR A 568 LEU A 492 ALA A 613 VAL A 518	None	1.36A	2g72A-2g9fA: undetectable	2g72A-2g9fA: 20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_A_ASDA1223_1 (GLUTATHIONE S-TRANSFERASE A2)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 8	ILE A 511 GLY A 517 LEU A 477 PHE A 478 PHE A 490	None None None GOL A 103 ( 4.7A) None	1.42A	2vctA-2g9fA: undetectable	2vctA-2g9fA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_B_ASDB1223_1 (GLUTATHIONE S-TRANSFERASE A2)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 8	ILE A 511 GLY A 517 LEU A 477 PHE A 478 PHE A 490	None None None GOL A 103 ( 4.7A) None	1.41A	2vctB-2g9fA: undetectable	2vctB-2g9fA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCT_D_ASDD1223_1 (GLUTATHIONE S-TRANSFERASE A2)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 7	ILE A 511 GLY A 517 LEU A 477 PHE A 478 PHE A 490	None None None GOL A 103 ( 4.7A) None	1.40A	2vctD-2g9fA: undetectable	2vctD-2g9fA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODO_A_FK5A205_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 10	LEU A 642 ILE A 548 LEU A 537 LEU A 611 PHE A 630	None	0.99A	4odoA-2g9fA: undetectable	4odoA-2g9fA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODO_B_FK5B203_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 10	LEU A 642 ILE A 548 LEU A 537 LEU A 611 PHE A 630	None	1.04A	4odoB-2g9fA: undetectable	4odoB-2g9fA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ODO_C_FK5C204_1 (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 10	LEU A 642 ILE A 548 LEU A 537 LEU A 611 PHE A 630	None	1.02A	4odoC-2g9fA: undetectable	4odoC-2g9fA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_A_29SA601_1 (ESTROGEN RECEPTOR)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 12	ALA A 613 GLU A 612 LEU A 611 TRP A 550 MET A 521	None	1.24A	4xi3A-2g9fA: undetectable	4xi3A-2g9fA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_A_29SA601_1 (ESTROGEN RECEPTOR)	2g9f	PEPTIDE N-GLYCANASE (Mus musculus)	5 / 12	ALA A 613 LEU A 611 TRP A 550 MET A 521 LEU A 537	None	1.30A	4xi3A-2g9fA: undetectable	4xi3A-2g9fA: 20.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2G72_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"TYR A 501;THR A 568;LEU A 492;ALA A 613;VAL A 518","None","1.36A","2g72A-2g9fA:undetectable","2g72A-2g9fA:20.07"],["2VCT_A_ASDA1223_1","GLUTATHIONE S-TRANSFERASE A2","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"ILE A 511;GLY A 517;LEU A 477;PHE A 478;PHE A 490","None;None;None;GOL A 103 ( 4.7A);None","1.42A","2vctA-2g9fA:undetectable","2vctA-2g9fA:23.21"],["2VCT_B_ASDB1223_1","GLUTATHIONE S-TRANSFERASE A2","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"ILE A 511;GLY A 517;LEU A 477;PHE A 478;PHE A 490","None;None;None;GOL A 103 ( 4.7A);None","1.41A","2vctB-2g9fA:undetectable","2vctB-2g9fA:23.21"],["2VCT_D_ASDD1223_1","GLUTATHIONE S-TRANSFERASE A2","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"ILE A 511;GLY A 517;LEU A 477;PHE A 478;PHE A 490","None;None;None;GOL A 103 ( 4.7A);None","1.40A","2vctD-2g9fA:undetectable","2vctD-2g9fA:23.21"],["4ODO_A_FK5A205_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"LEU A 642;ILE A 548;LEU A 537;LEU A 611;PHE A 630","None","0.99A","4odoA-2g9fA:undetectable","4odoA-2g9fA:17.65"],["4ODO_B_FK5B203_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"LEU A 642;ILE A 548;LEU A 537;LEU A 611;PHE A 630","None","1.04A","4odoB-2g9fA:undetectable","4odoB-2g9fA:17.65"],["4ODO_C_FK5C204_1","PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SLYD","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"LEU A 642;ILE A 548;LEU A 537;LEU A 611;PHE A 630","None","1.02A","4odoC-2g9fA:undetectable","4odoC-2g9fA:17.65"],["4XI3_A_29SA601_1","ESTROGEN RECEPTOR","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"ALA A 613;GLU A 612;LEU A 611;TRP A 550;MET A 521","None","1.24A","4xi3A-2g9fA:undetectable","4xi3A-2g9fA:20.16"],["4XI3_A_29SA601_1","ESTROGEN RECEPTOR","2g9f","PEPTIDE N-GLYCANASE","Mus musculus",5,"ALA A 613;LEU A 611;TRP A 550;MET A 521;LEU A 537","None","1.30A","4xi3A-2g9fA:undetectable","4xi3A-2g9fA:20.16"]]