SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2g9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 12 ILE D 139
LEU D 129
LEU D  99
ILE D 108
PHE D 161
 None
 1.03A 1bsxA-2g9hD:
undetectable		 1bsxA-2g9hD:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 12 ILE D 139
LEU D 129
LEU D  99
ILE D 108
PHE D 161
 None
 1.03A 1bsxB-2g9hD:
undetectable		 1bsxB-2g9hD:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		4 / 6 HIS D 105
PHE D 206
LEU D 208
ILE D  97
 None
 1.08A 1sbrA-2g9hD:
undetectable
1sbrB-2g9hD:
undetectable		 1sbrA-2g9hD:
19.91
1sbrB-2g9hD:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 12 ILE D 139
LEU D 129
LEU D  99
ILE D 108
PHE D 161
 None
 1.09A 1xzxX-2g9hD:
undetectable		 1xzxX-2g9hD:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 12 LEU D  24
PHE D  65
GLY D  81
ILE D 125
VAL D 127
 None
 1.31A 2zznA-2g9hD:
undetectable		 2zznA-2g9hD:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		4 / 8 HIS D 142
GLY D 141
ASN D 138
TYR D 153
 None
 1.13A 3ccfA-2g9hD:
undetectable		 3ccfA-2g9hD:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 12 ILE D 139
LEU D 129
LEU D  99
ILE D 108
PHE D 161
 None
 1.06A 3gwsX-2g9hD:
undetectable		 3gwsX-2g9hD:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		4 / 8 LEU D   9
ARG D  10
THR D  14
GLY D 164
 None
 0.82A 3ny4A-2g9hD:
undetectable		 3ny4A-2g9hD:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 11 GLN D 134
PHE D 157
GLY D 141
SER D 159
PHE D 181
 None
 1.50A 3v3nD-2g9hD:
undetectable		 3v3nD-2g9hD:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		4 / 6 ILE D 201
TYR D 195
TYR D 178
PHE D 168
 None
 1.09A 4g10A-2g9hD:
undetectable		 4g10A-2g9hD:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 12 ILE D 139
LEU D 129
LEU D  99
ILE D 108
PHE D 161
 None
 1.11A 4lnwA-2g9hD:
undetectable		 4lnwA-2g9hD:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		5 / 12 ILE D 139
LEU D 129
LEU D  99
ILE D 108
PHE D 161
 None
 1.12A 4lnxA-2g9hD:
undetectable		 4lnxA-2g9hD:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		4 / 6 GLN D 134
ASN D 143
SER D 159
PHE D 181
 None
 1.22A 6ekuA-2g9hD:
undetectable		 6ekuA-2g9hD:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		3 / 3 LEU D 133
LEU D 180
ARG D 130
 None
 0.68A 6fgcA-2g9hD:
undetectable		 6fgcA-2g9hD:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		3 / 3 LEU D 133
LEU D 180
ARG D 130
 None
 0.67A 6fgdA-2g9hD:
undetectable		 6fgdA-2g9hD:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 2g9h EXTRACELLULAR
ENTEROTOXIN TYPE I
(Staphylococcus
aureus) 		4 / 6 LEU D 192
VAL D 120
PHE D 168
PHE D 206
 None
 1.06A 6h7lA-2g9hD:
undetectable		 6h7lA-2g9hD:
16.19