SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ga0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IVU_A_ZD6A3015_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR)	2ga0	SURFACE PROTEIN VSPA (Borrelia turicatae)	3 / 3	ALA A 104 GLY A 97 SER A 67	None	0.49A	2ivuA-2ga0A: 3.4	2ivuA-2ga0A: 19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8X_A_NIMA701_2 (PROSTAGLANDIN G/H SYNTHASE 1)	2ga0	SURFACE PROTEIN VSPA (Borrelia turicatae)	3 / 3	VAL A 129 SER A 133 LEU A 109	None	0.65A	3n8xA-2ga0A: undetectable	3n8xA-2ga0A: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A3P_A_ACTA1223_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15)	2ga0	SURFACE PROTEIN VSPA (Borrelia turicatae)	4 / 5	ASP A 60 THR A 63 LEU A 64 LYS A 108	None	1.00A	4a3pA-2ga0A: undetectable	4a3pA-2ga0A: 22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDT_A_ACTA407_0 (FAD:PROTEIN FMN TRANSFERASE)	2ga0	SURFACE PROTEIN VSPA (Borrelia turicatae)	3 / 3	ASP A 87 GLY A 76 ASP A 154	NI A 14 (-2.4A) None None	0.70A	4xdtA-2ga0A: undetectable	4xdtA-2ga0A: 21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HP1_C_PPFC601_1 (HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT)	2ga0	SURFACE PROTEIN VSPA (Borrelia turicatae)	4 / 6	ASP A 154 GLY A 76 ASP A 89 LYS A 158	None	1.41A	5hp1C-2ga0A: undetectable	5hp1C-2ga0A: 17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	2ga0	SURFACE PROTEIN VSPA (Borrelia turicatae)	4 / 5	ILE A 68 SER A 67 ALA A 104 LEU A 137	None	0.94A	6dwnA-2ga0A: undetectable	6dwnA-2ga0A: 18.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2IVU_A_ZD6A3015_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR","2ga0","SURFACE PROTEIN VSPA","Borrelia turicatae",3,"ALA A 104;GLY A  97;SER A  67","None","0.49A","2ivuA-2ga0A:3.4","2ivuA-2ga0A:19.50"],["3N8X_A_NIMA701_2","PROSTAGLANDIN G\/H SYNTHASE 1","2ga0","SURFACE PROTEIN VSPA","Borrelia turicatae",3,"VAL A 129;SER A 133;LEU A 109","None","0.65A","3n8xA-2ga0A:undetectable","3n8xA-2ga0A:15.53"],["4A3P_A_ACTA1223_0","UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15","2ga0","SURFACE PROTEIN VSPA","Borrelia turicatae",4,"ASP A  60;THR A  63;LEU A  64;LYS A 108","None","1.00A","4a3pA-2ga0A:undetectable","4a3pA-2ga0A:22.83"],["4XDT_A_ACTA407_0","FAD:PROTEIN FMN TRANSFERASE","2ga0","SURFACE PROTEIN VSPA","Borrelia turicatae",3,"ASP A  87;GLY A  76;ASP A 154"," NI A  14 (-2.4A);None;None","0.70A","4xdtA-2ga0A:undetectable","4xdtA-2ga0A:21.26"],["5HP1_C_PPFC601_1","HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT","2ga0","SURFACE PROTEIN VSPA","Borrelia turicatae",4,"ASP A 154;GLY A  76;ASP A  89;LYS A 158","None","1.41A","5hp1C-2ga0A:undetectable","5hp1C-2ga0A:17.38"],["6DWN_A_AQ4A602_1","CYTOCHROME P450 1A1","2ga0","SURFACE PROTEIN VSPA","Borrelia turicatae",4,"ILE A  68;SER A  67;ALA A 104;LEU A 137","None","0.94A","6dwnA-2ga0A:undetectable","6dwnA-2ga0A:18.13"]]