SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 2gan 182AA LONG
HYPOTHETICAL PROTEIN
(Pyrococcus
horikoshii) 		4 / 6 VAL A   4
VAL A 113
ILE A  78
ARG A 134
 None
 1.12A 3ms9A-2ganA:
undetectable		 3ms9A-2ganA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 2gan 182AA LONG
HYPOTHETICAL PROTEIN
(Pyrococcus
horikoshii) 		3 / 3 ARG A  23
PRO A  44
PHE A  22
 None
 0.90A 3thrC-2ganA:
undetectable		 3thrC-2ganA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 2gan 182AA LONG
HYPOTHETICAL PROTEIN
(Pyrococcus
horikoshii) 		3 / 3 TYR A  72
LYS A   1
LYS A  74
 None
None
SO4  A1203 (-2.8A)
 1.25A 5dbyA-2ganA:
undetectable		 5dbyA-2ganA:
15.61