SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gax'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2L8M_A_CAMA415_0
(CAMPHOR
5-MONOOXYGENASE)		 2gax HYPOTHETICAL PROTEIN
ATU0240
(Agrobacterium
fabrum) 		5 / 9 LEU A  14
THR A  23
VAL A  60
ILE A   9
VAL A   8
 None
 1.35A 2l8mA-2gaxA:
undetectable		 2l8mA-2gaxA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2gax HYPOTHETICAL PROTEIN
ATU0240
(Agrobacterium
fabrum) 		5 / 11 ILE A  80
ILE A   6
VAL A 124
ILE A   9
MET A 115
 None
 1.12A 3b2rB-2gaxA:
undetectable		 3b2rB-2gaxA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA502_0
(RNA POLYMERASE
3D-POL)		 2gax HYPOTHETICAL PROTEIN
ATU0240
(Agrobacterium
fabrum) 		3 / 3 ARG A  74
LYS A 126
LYS A 129
 None
 1.07A 4k50A-2gaxA:
undetectable		 4k50A-2gaxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE502_0
(RNA POLYMERASE
3D-POL)		 2gax HYPOTHETICAL PROTEIN
ATU0240
(Agrobacterium
fabrum) 		3 / 3 ARG A  74
LYS A 126
LYS A 129
 None
 1.05A 4k50E-2gaxA:
undetectable		 4k50E-2gaxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI506_0
(RNA POLYMERASE
3D-POL)		 2gax HYPOTHETICAL PROTEIN
ATU0240
(Agrobacterium
fabrum) 		3 / 3 ARG A  74
LYS A 126
LYS A 129
 None
 1.04A 4k50I-2gaxA:
undetectable		 4k50I-2gaxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 2gax HYPOTHETICAL PROTEIN
ATU0240
(Agrobacterium
fabrum) 		4 / 4 THR A  82
LEU A  84
HIS A  72
GLY A 114
 None
 1.29A 5gwyA-2gaxA:
undetectable		 5gwyA-2gaxA:
16.56