SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gbb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P2K_B_SAMB6735_0 (16S RRNA METHYLASE)	2gbb	PUTATIVE CHORISMATE MUTASE (Yersinia pestis)	5 / 12	GLY A 82 ALA A 74 LEU A 145 THR A 135 LEU A 138	None	1.15A	3p2kB-2gbbA: undetectable	3p2kB-2gbbA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RAE_F_LFXF101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B)	2gbb	PUTATIVE CHORISMATE MUTASE (Yersinia pestis)	3 / 4	SER A 80 GLY A 131 GLU A 42	None	0.69A	3raeA-2gbbA: undetectable 3raeC-2gbbA: undetectable	3raeA-2gbbA: 16.49 3raeC-2gbbA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4JUO_F_LFXF101_1 (DNA TOPOISOMERASE 4 SUBUNIT A DNA TOPOISOMERASE 4 SUBUNIT B E-SITE DNA)	2gbb	PUTATIVE CHORISMATE MUTASE (Yersinia pestis)	3 / 4	SER A 80 GLY A 131 GLU A 42	None	0.61A	4juoA-2gbbA: 2.8 4juoC-2gbbA: undetectable	4juoA-2gbbA: 16.49 4juoC-2gbbA: 13.36