SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gbz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ILE A  29
ILE A  51
ARG A  77
LEU A 119
ILE A  14
 None
 0.88A 1bsxA-2gbzA:
undetectable		 1bsxA-2gbzA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ILE A  29
ILE A  51
ARG A  77
LEU A 119
ILE A  14
 None
 0.89A 1bsxB-2gbzA:
undetectable		 1bsxB-2gbzA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 8 ASP A 169
ILE A  34
ILE A 171
GLY A 109
ILE A 112
 None
 1.16A 1sh9A-2gbzA:
undetectable		 1sh9A-2gbzA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ILE A  29
ILE A  51
ARG A  77
LEU A 119
ILE A  14
 None
 0.91A 2h79A-2gbzA:
undetectable		 2h79A-2gbzA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		4 / 6 ALA A 163
ASP A  15
GLU A  30
ARG A  77
 None
MG  A5082 (-2.6A)
None
None
 1.41A 2ouzA-2gbzA:
undetectable		 2ouzA-2gbzA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ILE A  29
ILE A  51
ARG A  77
LEU A 119
ILE A  14
 None
 0.94A 3gwsX-2gbzA:
undetectable		 3gwsX-2gbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_B_PXLB400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ASP A 169
SER A 165
SER A 158
HIS A 161
GLN A  68
 None
 1.41A 3mbhB-2gbzA:
undetectable		 3mbhB-2gbzA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_C_PXLC400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ASP A 169
SER A 165
SER A 158
HIS A 161
GLN A  68
 None
 1.43A 3mbhC-2gbzA:
undetectable		 3mbhC-2gbzA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_D_PXLD400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ASP A 169
SER A 165
SER A 158
HIS A 161
GLN A  68
 None
 1.43A 3mbhD-2gbzA:
undetectable		 3mbhD-2gbzA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBH_E_PXLE400_1
(PUTATIVE
PHOSPHOMETHYLPYRIMID
INE KINASE)		 2gbz OLIGORIBONUCLEASE
(Xanthomonas
campestris) 		5 / 12 ASP A 169
SER A 165
SER A 158
HIS A 161
GLN A  68
 None
 1.38A 3mbhE-2gbzA:
undetectable		 3mbhE-2gbzA:
21.13