SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 2gd5 CHARGED
MULTIVESICULAR BODY
PROTEIN 3
(Homo
sapiens) 		3 / 3 MET A 127
LEU A 130
SER A 131
 None
 0.69A 1ee2A-2gd5A:
undetectable		 1ee2A-2gd5A:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 2gd5 CHARGED
MULTIVESICULAR BODY
PROTEIN 3
(Homo
sapiens) 		5 / 12 LEU A 104
GLY A  90
ILE A 140
ALA A 137
ILE A 139
 None
 0.88A 2rkfB-2gd5A:
undetectable		 2rkfB-2gd5A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2gd5 CHARGED
MULTIVESICULAR BODY
PROTEIN 3
(Homo
sapiens) 		4 / 8 MET A 114
LEU A 117
GLU A 122
LEU A 130
 None
 1.20A 5dxeA-2gd5A:
undetectable		 5dxeA-2gd5A:
20.00