SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		4 / 8 LEU A  14
PHE A  43
GLY A  39
TYR A 124
 EDO  A 191 ( 4.1A)
None
None
None
 0.96A 1fapB-2gd9A:
undetectable		 1fapB-2gd9A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		4 / 8 PHE A  88
ILE A 106
LEU A  51
VAL A 110
 None
 0.87A 1fslA-2gd9A:
undetectable		 1fslA-2gd9A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		4 / 5 LEU A 151
PRO A 148
VAL A 149
ASP A  30
 None
 0.77A 3ufnA-2gd9A:
undetectable
3ufnB-2gd9A:
undetectable		 3ufnA-2gd9A:
19.37
3ufnB-2gd9A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		4 / 5 ASP A 120
GLY A 118
ASP A  48
THR A  49
 None
 1.26A 3vqrB-2gd9A:
undetectable		 3vqrB-2gd9A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		3 / 3 ARG A 173
ARG A 143
ASP A  42
 None
 0.97A 3wipG-2gd9A:
undetectable
3wipH-2gd9A:
undetectable		 3wipG-2gd9A:
18.06
3wipH-2gd9A:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		5 / 11 ALA A 127
SER A 128
PHE A 142
ILE A 134
ASN A 135
 PO4  A 190 ( 3.7A)
PO4  A 190 (-2.6A)
None
None
None
 1.37A 4bb2A-2gd9A:
undetectable
4bb2B-2gd9A:
undetectable		 4bb2A-2gd9A:
21.45
4bb2B-2gd9A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		4 / 7 VAL A 161
ASN A 135
GLY A 137
PHE A 142
 None
 0.98A 4ejjB-2gd9A:
undetectable		 4ejjB-2gd9A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		5 / 11 PHE A 101
GLY A 126
GLY A 125
GLU A  23
ILE A  22
 None
CL  A 189 (-3.9A)
EDO  A 191 ( 4.4A)
PO4  A 190 (-4.0A)
EDO  A 191 (-3.8A)
 1.34A 4zvmA-2gd9A:
undetectable
4zvmB-2gd9A:
undetectable		 4zvmA-2gd9A:
20.59
4zvmB-2gd9A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		4 / 6 GLU A 108
GLY A 126
ARG A  90
GLY A  53
 None
CL  A 189 (-3.9A)
PO4  A 190 ( 3.8A)
CL  A 189 (-3.4A)
 0.91A 5cdnC-2gd9A:
undetectable
5cdnD-2gd9A:
2.2		 5cdnC-2gd9A:
17.30
5cdnD-2gd9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		3 / 3 ARG A   8
THR A  49
ASP A  48
 None
 0.90A 5g5gA-2gd9A:
undetectable
5g5gB-2gd9A:
undetectable		 5g5gA-2gd9A:
20.08
5g5gB-2gd9A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 2gd9 HYPOTHETICAL PROTEIN
YYAP
(Bacillus
subtilis) 		4 / 6 PHE A  57
LEU A  51
SER A  56
GLY A 125
 None
None
None
EDO  A 191 ( 4.4A)
 1.11A 5o4yF-2gd9A:
undetectable		 5o4yF-2gd9A:
5.84