SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2gdf LECTIN
(Dioclea
violacea) 		3 / 3 ALA A 177
VAL A  89
TRP A  88
 None
 0.95A 1jo4A-2gdfA:
undetectable		 1jo4A-2gdfA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2gdf LECTIN
(Dioclea
violacea) 		3 / 3 ALA A 177
VAL A  89
TRP A  88
 None
 0.95A 1jo4B-2gdfA:
undetectable		 1jo4B-2gdfA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2gdf LECTIN
(Dioclea
violacea) 		5 / 10 LEU A 230
ALA A   6
ILE A   4
HIS A  24
ASP A  19
 None
 1.30A 2b17A-2gdfA:
undetectable		 2b17A-2gdfA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1414_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 8 LEU A 156
ILE A 210
LEU A  93
LEU A 154
 None
 0.80A 2xfhA-2gdfA:
undetectable		 2xfhA-2gdfA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_B_D2VB602_1
(CYTOCHROME P450 2R1)		 2gdf LECTIN
(Dioclea
violacea) 		5 / 12 THR A  37
ALA A  63
VAL A  65
THR A  96
ILE A  32
 None
 1.15A 3czhB-2gdfA:
undetectable		 3czhB-2gdfA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 6 ILE A  32
HIS A  24
LEU A 230
ASP A  28
 None
 1.23A 3oi8A-2gdfA:
undetectable		 3oi8A-2gdfA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 6 VAL A  65
TRP A  40
PHE A 195
GLU A   8
 None
 1.35A 4v3wA-2gdfA:
0.0
4v3wB-2gdfA:
0.0		 4v3wA-2gdfA:
19.48
4v3wB-2gdfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2gdf LECTIN
(Dioclea
violacea) 		3 / 3 HIS A 180
GLU A  87
TRP A  88
 None
 1.23A 5odiD-2gdfA:
undetectable		 5odiD-2gdfA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2gdf LECTIN
(Dioclea
violacea) 		3 / 3 GLY A 209
THR A  97
ASN A 104
 None
 0.68A 5odiG-2gdfA:
undetectable		 5odiG-2gdfA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 2gdf LECTIN
(Dioclea
violacea) 		5 / 12 ALA A   6
LEU A  81
ILE A 181
VAL A  91
PHE A 111
 None
 1.35A 5vlmB-2gdfA:
undetectable		 5vlmB-2gdfA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_0
(REGULATORY PROTEIN
TETR)		 2gdf LECTIN
(Dioclea
violacea) 		5 / 12 ALA A 215
LEU A  81
VAL A 179
ASP A 192
PHE A 111
 None
 1.41A 5vlmD-2gdfA:
undetectable		 5vlmD-2gdfA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 6 PHE A 233
ARG A 228
LEU A 230
ALA A   6
 None
 0.98A 6b89B-2gdfA:
undetectable		 6b89B-2gdfA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 5 LEU A   9
THR A 105
PRO A 206
ARG A 204
 None
 1.38A 6ew0B-2gdfA:
undetectable		 6ew0B-2gdfA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 5 LEU A   9
THR A 105
PRO A 206
ARG A 204
 None
 1.38A 6ew0D-2gdfA:
undetectable		 6ew0D-2gdfA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 5 LEU A   9
THR A 105
PRO A 206
ARG A 204
 None
 1.38A 6ew0H-2gdfA:
undetectable		 6ew0H-2gdfA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 2gdf LECTIN
(Dioclea
violacea) 		4 / 5 LEU A   9
THR A 105
PRO A 206
ARG A 204
 None
 1.37A 6ew0I-2gdfA:
undetectable		 6ew0I-2gdfA:
17.09