SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gdq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 2gdq YITF
(Bacillus
subtilis) 		4 / 5 LEU A 100
THR A 101
ARG A  78
VAL A  82
 None
 1.11A 1ekjF-2gdqA:
undetectable
1ekjG-2gdqA:
undetectable		 1ekjF-2gdqA:
18.94
1ekjG-2gdqA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 2gdq YITF
(Bacillus
subtilis) 		5 / 12 TYR A 127
ILE A 158
VAL A 147
VAL A 160
LEU A 177
 None
 0.83A 1vptA-2gdqA:
undetectable		 1vptA-2gdqA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 2gdq YITF
(Bacillus
subtilis) 		5 / 12 ARG A 142
ASP A 190
ILE A 162
GLY A 163
GLY A 164
 None
 1.00A 2o4kA-2gdqA:
undetectable		 2o4kA-2gdqA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 2gdq YITF
(Bacillus
subtilis) 		3 / 3 MET A 245
VAL A  52
GLU A 326
 None
 0.88A 2x9gA-2gdqA:
undetectable		 2x9gA-2gdqA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2gdq YITF
(Bacillus
subtilis) 		4 / 8 GLN A 264
ASP A 261
TYR A 228
CYH A 259
 None
 1.30A 2xz5A-2gdqA:
undetectable
2xz5C-2gdqA:
undetectable		 2xz5A-2gdqA:
20.42
2xz5C-2gdqA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 2gdq YITF
(Bacillus
subtilis) 		3 / 3 LEU A 260
VAL A 237
ARG A 232
 None
 0.85A 3b0wB-2gdqA:
undetectable		 3b0wB-2gdqA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 2gdq YITF
(Bacillus
subtilis) 		5 / 10 ARG A 142
ASP A 190
ILE A 162
GLY A 163
GLY A 164
 None
 1.04A 3em4V-2gdqA:
undetectable		 3em4V-2gdqA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 2gdq YITF
(Bacillus
subtilis) 		5 / 11 LEU A  36
GLY A 297
ILE A  37
SER A  94
VAL A  52
 None
 1.21A 3gyqB-2gdqA:
undetectable		 3gyqB-2gdqA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 2gdq YITF
(Bacillus
subtilis) 		3 / 3 LYS A  64
VAL A  60
HIS A  59
 None
 1.05A 3tj7A-2gdqA:
undetectable		 3tj7A-2gdqA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 2gdq YITF
(Bacillus
subtilis) 		3 / 3 PHE A 334
ASP A 328
ARG A  32
 None
 0.88A 4eahF-2gdqA:
undetectable		 4eahF-2gdqA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 2gdq YITF
(Bacillus
subtilis) 		3 / 3 PHE A 334
ASP A 328
ARG A  32
 None
 0.87A 4eahG-2gdqA:
undetectable		 4eahG-2gdqA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 2gdq YITF
(Bacillus
subtilis) 		4 / 5 TYR A 195
PRO A 221
LEU A 231
TYR A 228
 None
 1.43A 4w5qA-2gdqA:
0.0		 4w5qA-2gdqA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 2gdq YITF
(Bacillus
subtilis) 		4 / 6 TYR A 195
PRO A 221
LEU A 231
TYR A 228
 None
 1.40A 4z4cA-2gdqA:
undetectable		 4z4cA-2gdqA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gdq YITF
(Bacillus
subtilis) 		3 / 3 ARG A 289
VAL A 239
TRP A 215
 None
 1.25A 5fvoA-2gdqA:
undetectable		 5fvoA-2gdqA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2gdq YITF
(Bacillus
subtilis) 		5 / 12 VAL A 144
GLU A 148
ASP A 170
HIS A 173
ALA A 176
 None
 1.37A 5hnzB-2gdqA:
2.3		 5hnzB-2gdqA:
22.03