SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 12 ASP A 192
ALA A 193
HIS A 289
ASP A 290
ARG A 403
 SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 ( 4.9A)
 0.51A 1dedA-2gduA:
26.5		 1dedA-2gduA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ARG A 403
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 ( 4.9A)
 0.54A 1dedB-2gduA:
24.3		 1dedB-2gduA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 7 ALA A 364
TYR A 350
SER A 264
ALA A 262
 None
 1.07A 1k5qA-2gduA:
undetectable
1k5qB-2gduA:
undetectable		 1k5qA-2gduA:
16.67
1k5qB-2gduA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_1
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 4 ILE A 229
LEU A 227
VAL A 186
ALA A  72
 None
 1.00A 1mz9A-2gduA:
undetectable		 1mz9A-2gduA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 5 ILE A 229
LEU A 227
VAL A 186
ALA A  72
 None
 0.88A 1mz9C-2gduA:
undetectable		 1mz9C-2gduA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		3 / 3 LEU A 415
VAL A 420
LEU A 423
 None
 0.53A 1mz9B-2gduA:
undetectable		 1mz9B-2gduA:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 5 VAL A 374
GLY A 373
VAL A 283
TRP A 274
 None
 1.36A 1tkqB-2gduA:
undetectable		 1tkqB-2gduA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 9 TYR A 350
LEU A 371
PHE A 452
LEU A 255
LEU A 258
 None
 1.28A 2bxeA-2gduA:
undetectable		 2bxeA-2gduA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 6 LEU A 341
ALA A  49
HIS A  88
ASP A 162
 SUC  A2064 (-4.7A)
None
SUC  A2064 (-3.9A)
None
 1.13A 2dpzA-2gduA:
undetectable		 2dpzA-2gduA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 10 SER A 330
ILE A 322
ILE A 292
LEU A 318
ASN A 317
 None
 1.18A 2nnhB-2gduA:
undetectable		 2nnhB-2gduA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A 127
THR A 208
PRO A 209
 None
 0.52A 2pynB-2gduA:
undetectable		 2pynB-2gduA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A 127
THR A 208
PRO A 209
 None
 0.47A 2q64B-2gduA:
undetectable		 2q64B-2gduA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A 127
THR A 208
PRO A 209
 None
 0.53A 2qakB-2gduA:
undetectable		 2qakB-2gduA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 8 ARG A 190
GLN A 376
ARG A 249
GLN A 240
 SUC  A2064 (-3.4A)
None
None
None
 1.50A 2vxaH-2gduA:
undetectable
2vxaI-2gduA:
undetectable
2vxaJ-2gduA:
undetectable		 2vxaH-2gduA:
9.69
2vxaI-2gduA:
9.69
2vxaJ-2gduA:
9.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 6 TYR A 378
PHE A  30
TYR A  34
LEU A  14
 None
 1.11A 2w98A-2gduA:
undetectable
2w98B-2gduA:
undetectable		 2w98A-2gduA:
19.84
2w98B-2gduA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 6 ILE A 362
ARG A 469
THR A 464
LEU A 463
 None
 0.75A 3ag1N-2gduA:
undetectable
3ag1W-2gduA:
undetectable		 3ag1N-2gduA:
22.71
3ag1W-2gduA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.65A 3aicA-2gduA:
7.0		 3aicA-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.67A 3aicB-2gduA:
5.3		 3aicB-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.66A 3aicC-2gduA:
4.9		 3aicC-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.70A 3aicD-2gduA:
4.9		 3aicD-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.70A 3aicE-2gduA:
7.0		 3aicE-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.65A 3aicF-2gduA:
7.1		 3aicF-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.65A 3aicG-2gduA:
7.0		 3aicG-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 190
ASP A 192
ALA A 193
HIS A 289
ASP A 290
ASP A  50
 SUC  A2064 (-3.4A)
SUC  A2064 (-3.1A)
SUC  A2064 (-3.6A)
SUC  A2064 (-3.7A)
SUC  A2064 (-2.9A)
SUC  A2064 (-2.6A)
 0.70A 3aicH-2gduA:
5.8		 3aicH-2gduA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 12 THR A 334
GLY A 398
ASN A 397
GLY A 328
HIS A 323
 None
 1.18A 3eeyJ-2gduA:
undetectable		 3eeyJ-2gduA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_B_KKKB413_1
(FLAVOHEMOGLOBIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 12 HIS A 360
GLN A 359
ALA A 480
LEU A 371
GLY A 470
 None
 1.11A 3ozwB-2gduA:
undetectable		 3ozwB-2gduA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_C_NCAC302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 10 TYR A 378
TYR A 379
ALA A  51
ASP A 400
TYR A  10
 None
 1.33A 3rodC-2gduA:
0.3		 3rodC-2gduA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		3 / 3 ASP A 127
THR A 208
PRO A 209
 None
 0.49A 3tkgD-2gduA:
undetectable		 3tkgD-2gduA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 8 ILE A 131
THR A 165
LEU A 113
VAL A 118
 None
 0.88A 3ua5A-2gduA:
undetectable		 3ua5A-2gduA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 7 ILE A 131
THR A 165
LEU A 113
VAL A 118
 None
 0.84A 3ua5B-2gduA:
undetectable		 3ua5B-2gduA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 6 TYR A 109
ARG A 150
ASP A 164
GLU A 200
 None
 1.24A 4ax8A-2gduA:
undetectable		 4ax8A-2gduA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_1
(WBDD)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 6 TYR A 109
ARG A 150
ASP A 164
GLU A 200
 None
 1.27A 4azvA-2gduA:
undetectable		 4azvA-2gduA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7B_B_TCWB1126_1
(TRANSTHYRETIN)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 7 LEU A 463
ALA A 480
LEU A 482
SER A 493
 None
 0.91A 4d7bA-2gduA:
undetectable		 4d7bA-2gduA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_A_ADNA401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 365
LEU A 286
GLN A 368
PRO A 256
PRO A 257
PHE A 253
 None
 1.44A 4o8jA-2gduA:
0.0		 4o8jA-2gduA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8J_B_ADNB401_1
(RNA 3'-TERMINAL
PHOSPHATE CYCLASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		6 / 12 ARG A 365
LEU A 286
GLN A 368
PRO A 256
PRO A 257
PHE A 253
 None
 1.44A 4o8jB-2gduA:
0.0		 4o8jB-2gduA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_1
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 5 TYR A 251
ASP A 290
ASP A 400
TYR A  10
 None
SUC  A2064 (-2.9A)
None
None
 1.40A 4qdjA-2gduA:
undetectable		 4qdjA-2gduA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 4 ILE A 401
ASN A 402
ILE A 292
VAL A 346
 None
 1.29A 4uy87-2gduA:
undetectable		 4uy87-2gduA:
3.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		3 / 3 MET A   1
GLU A 228
LEU A 230
 None
 0.69A 4v2oB-2gduA:
undetectable		 4v2oB-2gduA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 5 TYR A 196
PHE A 140
LEU A 113
PRO A 139
 None
 1.49A 5csyB-2gduA:
16.4		 5csyB-2gduA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 5 ASP A  12
ILE A 411
ASN A 397
TYR A 405
 None
 1.24A 6a93B-2gduA:
undetectable		 6a93B-2gduA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_1
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 10 LEU A  40
HIS A  38
TYR A 378
PHE A 253
VAL A 283
 None
 1.34A 6b89A-2gduA:
1.0		 6b89A-2gduA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 12 HIS A 234
PHE A 253
ARG A 365
GLY A 381
GLY A 293
 SUC  A2064 (-3.9A)
None
None
None
None
 1.09A 6brdB-2gduA:
undetectable		 6brdB-2gduA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		5 / 12 LEU A 341
GLY A 197
ASP A  50
ASN A 347
GLN A 232
 SUC  A2064 (-4.7A)
None
SUC  A2064 (-2.6A)
None
SUC  A2064 (-2.7A)
 0.97A 6gngA-2gduA:
undetectable		 6gngA-2gduA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_E_PCFE202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2gdu SUCROSE
PHOSPHORYLASE
(Bifidobacterium
adolescentis) 		4 / 8 TYR A 251
VAL A  82
ARG A 190
ASP A 290
 None
None
SUC  A2064 (-3.4A)
SUC  A2064 (-2.9A)
 1.02A 6hu9a-2gduA:
undetectable
6hu9e-2gduA:
undetectable		 6hu9a-2gduA:
21.59
6hu9e-2gduA:
14.98