SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ge3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA1_1
(CYTOCHROME P450 2D6)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 111
PHE A 168
PHE A 117
LEU A 119
PHE A  61
 None
 1.16A 3tbgA-2ge3A:
undetectable		 3tbgA-2ge3A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC1_1
(CYTOCHROME P450 2D6)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 111
PHE A 168
PHE A 117
LEU A 119
PHE A  61
 None
 1.18A 3tbgC-2ge3A:
undetectable		 3tbgC-2ge3A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		5 / 12 ARG A  76
GLY A  90
MET A  91
SER A 125
TYR A 137
 None
None
ACO  A1301 (-3.9A)
None
None
 1.45A 4kowA-2ge3A:
17.4		 4kowA-2ge3A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		5 / 12 LEU A 124
LEU A  89
GLY A  90
LEU A  35
HIS A 127
 None
None
None
ACO  A1301 (-4.8A)
None
 1.30A 4olmA-2ge3A:
undetectable		 4olmA-2ge3A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		3 / 3 LEU A 106
ARG A 109
ARG A 105
 None
 0.93A 4yiaB-2ge3A:
undetectable		 4yiaB-2ge3A:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		5 / 8 ILE A  54
VAL A  50
VAL A  28
ILE A  93
ILE A  70
 None
None
None
ACO  A1301 (-4.0A)
None
 1.49A 5hi2A-2ge3A:
undetectable		 5hi2A-2ge3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 TYR A  97
VAL A   8
ILE A  10
ALA A  63
 None
 0.75A 5ospA-2ge3A:
undetectable		 5ospA-2ge3A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		4 / 7 TYR A  97
VAL A   8
ILE A  10
ALA A  63
 None
 0.75A 5osrA-2ge3A:
undetectable		 5osrA-2ge3A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 2ge3 PROBABLE
ACETYLTRANSFERASE
(Agrobacterium
tumefaciens) 		3 / 3 PHE A  61
ASP A  74
LEU A  94
 None
 0.80A 5uhbC-2ge3A:
1.8		 5uhbC-2ge3A:
9.10