SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gee'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 2gee HYPOTHETICAL PROTEIN
(Homo
sapiens) 		4 / 8 GLU A 231
ARG A 219
LEU A 217
GLU A 264
 None
 0.79A 1cmaA-2geeA:
undetectable
1cmaB-2geeA:
undetectable		 1cmaA-2geeA:
17.93
1cmaB-2geeA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 2gee HYPOTHETICAL PROTEIN
(Homo
sapiens) 		6 / 11 GLY A 148
ASP A 141
GLY A 124
ILE A 122
THR A 177
VAL A 165
 None
 1.47A 1t7jA-2geeA:
undetectable		 1t7jA-2geeA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 2gee HYPOTHETICAL PROTEIN
(Homo
sapiens) 		4 / 8 TYR A 166
TRP A 114
LEU A 100
LEU A 112
 None
 1.04A 4jtrA-2geeA:
undetectable		 4jtrA-2geeA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 2gee HYPOTHETICAL PROTEIN
(Homo
sapiens) 		5 / 11 GLY A 148
ASP A 141
GLY A 124
ILE A 122
THR A 177
 None
 1.00A 4njvB-2geeA:
undetectable		 4njvB-2geeA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 2gee HYPOTHETICAL PROTEIN
(Homo
sapiens) 		4 / 8 SER A 101
PHE A 102
GLY A 111
THR A 178
 None
 0.90A 5flcB-2geeA:
undetectable		 5flcB-2geeA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 2gee HYPOTHETICAL PROTEIN
(Homo
sapiens) 		4 / 8 SER A 101
PHE A 102
GLY A 111
THR A 178
 None
 0.89A 5flcF-2geeA:
undetectable		 5flcF-2geeA:
11.11