SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gef'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 2gef PROTEASE VP4
(Blotched
snakehead
virus) 		4 / 5 GLU A 749
THR A 751
HIS A 762
HIS A 734
 None
 1.41A 1d4fD-2gefA:
undetectable		 1d4fD-2gefA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 2gef PROTEASE VP4
(Blotched
snakehead
virus) 		5 / 9 VAL A 591
VAL A 592
GLY A 690
SER A 692
LYS A 729
 None
 0.56A 4fwdA-2gefA:
10.9		 4fwdA-2gefA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 2gef PROTEASE VP4
(Blotched
snakehead
virus) 		4 / 6 LEU A 728
LEU A 603
THR A 712
VAL A 723
 None
 0.99A 4udaA-2gefA:
undetectable		 4udaA-2gefA:
19.92