SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gex'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 2gex SNOL
(Streptomyces
nogalater) 		4 / 8 HIS A  86
ALA A  84
VAL A 100
LEU A 145
 None
 0.88A 2it4A-2gexA:
undetectable		 2it4A-2gexA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2gex SNOL
(Streptomyces
nogalater) 		5 / 11 PRO A 136
ASP A 137
LEU A 141
VAL A 100
THR A  96
 None
 1.32A 3n23C-2gexA:
undetectable		 3n23C-2gexA:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2gex SNOL
(Streptomyces
nogalater) 		4 / 8 VAL A  25
VAL A 116
TRP A  29
TRP A  17
 None
 1.22A 3nlqA-2gexA:
undetectable
3nlqB-2gexA:
undetectable		 3nlqA-2gexA:
14.59
3nlqB-2gexA:
14.59