SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gez'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 1c9sL-2gezB:
undetectable
1c9sM-2gezB:
undetectable
1c9sL-2gezB:
20.15
1c9sM-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 1c9sM-2gezB:
undetectable
1c9sN-2gezB:
undetectable
1c9sM-2gezB:
20.15
1c9sN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 1c9sR-2gezB:
undetectable
1c9sS-2gezB:
undetectable
1c9sR-2gezB:
20.15
1c9sS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 1c9sS-2gezB:
undetectable
1c9sT-2gezB:
undetectable
1c9sS-2gezB:
20.15
1c9sT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 1gtfA-2gezB:
undetectable
1gtfB-2gezB:
undetectable
1gtfA-2gezB:
20.15
1gtfB-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 1gtfM-2gezB:
undetectable
1gtfN-2gezB:
undetectable
1gtfM-2gezB:
20.15
1gtfN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 8 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.41A 1gtfN-2gezB:
undetectable
1gtfO-2gezB:
undetectable
1gtfN-2gezB:
20.15
1gtfO-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 1gtfO-2gezB:
undetectable
1gtfP-2gezB:
undetectable
1gtfO-2gezB:
20.15
1gtfP-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.41A 1gtfP-2gezB:
undetectable
1gtfQ-2gezB:
undetectable
1gtfP-2gezB:
20.15
1gtfQ-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 1gtfT-2gezB:
undetectable
1gtfU-2gezB:
undetectable
1gtfT-2gezB:
20.15
1gtfU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.41A 1gtfL-2gezB:
undetectable
1gtfV-2gezB:
undetectable
1gtfL-2gezB:
20.15
1gtfV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.33A 1gtnG-2gezB:
undetectable
1gtnH-2gezB:
undetectable
1gtnG-2gezB:
20.15
1gtnH-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 1gtnN-2gezB:
undetectable
1gtnO-2gezB:
undetectable
1gtnN-2gezB:
20.15
1gtnO-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 1gtnO-2gezB:
undetectable
1gtnP-2gezB:
undetectable
1gtnO-2gezB:
20.15
1gtnP-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 1gtnQ-2gezB:
undetectable
1gtnR-2gezB:
undetectable
1gtnQ-2gezB:
20.15
1gtnR-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 1gtnR-2gezB:
undetectable
1gtnS-2gezB:
undetectable
1gtnR-2gezB:
20.15
1gtnS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.39A 1gtnS-2gezB:
undetectable
1gtnT-2gezB:
undetectable
1gtnS-2gezB:
20.15
1gtnT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 11 GLY B 195
HIS A   9
ALA A  67
THR B 225
GLY B 244
None
None
NA  A 401 (-4.6A)
None
None
1.12A 1gtnT-2gezB:
undetectable
1gtnU-2gezB:
undetectable
1gtnT-2gezB:
20.15
1gtnU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT

(Lupinus
luteus)
5 / 9 LEU A 103
GLU A  58
ILE A  69
VAL A  79
MET A  81
None
1.44A 1gx8A-2gezA:
undetectable
1gx8A-2gezA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 11 ILE B 289
GLY B 287
THR B 243
HIS A   9
GLY B 305
None
1.22A 1i7qA-2gezB:
undetectable
1i7qA-2gezB:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 ILE B 289
GLY B 287
THR B 243
HIS A   9
GLY B 305
None
1.20A 1i7qC-2gezB:
undetectable
1i7qC-2gezB:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 11 PHE B 307
LEU A  59
HIS A   9
ALA A  12
GLY B 305
None
1.32A 1l5rA-2gezB:
undetectable
1l5rA-2gezB:
11.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)
2gez L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 9 GLY B 287
PRO B 282
GLU B 248
GLY B 246
ASP B 224
None
None
None
CL  B 406 ( 3.8A)
None
1.12A 1mxdA-2gezB:
undetectable
1mxdA-2gezB:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)
2gez L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 11 GLY B 287
PRO B 282
GLU B 248
GLY B 246
ASP B 224
None
None
None
CL  B 406 ( 3.8A)
None
1.11A 1mxgA-2gezB:
undetectable
1mxgA-2gezB:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
4 / 6 GLY B 315
VAL A  39
ALA B 311
SER B 317
None
0.99A 1p6kA-2gezB:
undetectable
1p6kA-2gezB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 1utdN-2gezB:
undetectable
1utdO-2gezB:
undetectable
1utdN-2gezB:
20.15
1utdO-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.43A 1utdR-2gezB:
undetectable
1utdS-2gezB:
undetectable
1utdR-2gezB:
20.15
1utdS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT

(Lupinus
luteus)
5 / 10 GLY A  68
THR A 145
ASN A 148
VAL A  72
HIS A  64
NA  A 401 ( 4.6A)
None
None
None
None
1.24A 1v3qE-2gezA:
undetectable
1v3qE-2gezA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 11 ILE A  15
GLY B 287
THR B 243
HIS A   9
GLY A  13
None
1.16A 2fn1A-2gezA:
undetectable
2fn1A-2gezA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 11 ILE A  15
GLY B 287
THR B 243
HIS A   9
GLY A  13
None
1.17A 2fn1B-2gezA:
undetectable
2fn1B-2gezA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
4 / 8 ARG B 251
PRO B 226
SER A  97
GLY B 246
None
None
None
CL  B 406 ( 3.8A)
0.85A 2qd3A-2gezB:
undetectable
2qd3A-2gezB:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_B_TOPB1189_1
(DIHYDROFOLATE
REDUCTASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 10 ILE B 289
PHE A  65
THR B 303
ILE A  15
THR B 209
None
1.25A 2w3aB-2gezB:
undetectable
2w3aB-2gezB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 12 THR B 193
GLY A  10
GLY A  68
LEU A   8
THR B 209
None
None
NA  A 401 ( 4.6A)
None
None
1.15A 3eeyH-2gezB:
undetectable
3eeyH-2gezB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 12 THR B 193
GLY A  10
GLY A  68
LEU A   8
THR B 209
None
None
NA  A 401 ( 4.6A)
None
None
1.16A 3eeyI-2gezB:
undetectable
3eeyI-2gezB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
4 / 4 GLY A  38
VAL A  51
GLY B 195
THR B 209
None
0.89A 3ib2A-2gezA:
undetectable
3ib2A-2gezA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)
2gez L-ASPARAGINASE ALPHA
SUBUNIT

(Lupinus
luteus)
5 / 10 PRO A 105
LEU A 143
SER A  71
SER A  97
GLY A  98
None
1.25A 3iluB-2gezA:
undetectable
3iluE-2gezA:
undetectable
3iluB-2gezA:
20.23
3iluE-2gezA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)
2gez L-ASPARAGINASE ALPHA
SUBUNIT

(Lupinus
luteus)
5 / 11 SER A  97
GLY A  98
PRO A 105
LEU A 143
SER A  71
None
1.25A 3iluB-2gezA:
undetectable
3iluE-2gezA:
undetectable
3iluB-2gezA:
20.23
3iluE-2gezA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)
2gez L-ASPARAGINASE ALPHA
SUBUNIT

(Lupinus
luteus)
3 / 3 GLU A 136
GLU A  60
ASN A  61
None
0.90A 3lp9B-2gezA:
undetectable
3lp9D-2gezA:
undetectable
3lp9B-2gezA:
21.37
3lp9D-2gezA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT

(Lupinus
luteus)
3 / 3 ASN A  61
GLU A  58
ARG A  57
None
0.89A 3wxoA-2gezA:
undetectable
3wxoA-2gezA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
4 / 8 GLY B 246
GLY B 244
VAL B 254
HIS A   9
CL  B 406 ( 3.8A)
None
None
None
0.76A 4c5nC-2gezB:
undetectable
4c5nC-2gezB:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
4 / 7 ASN A 148
ARG A 151
LEU A 152
GLY B 212
None
1.00A 4cp3A-2gezA:
undetectable
4cp3B-2gezA:
undetectable
4cp3A-2gezA:
23.08
4cp3B-2gezA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
4 / 7 ASN A 148
ARG A 151
LEU A 152
GLY B 213
None
None
None
CL  B 406 (-3.7A)
0.94A 4cp3A-2gezA:
undetectable
4cp3B-2gezA:
undetectable
4cp3A-2gezA:
23.08
4cp3B-2gezA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 11 SER B 207
GLY B 195
VAL A  56
SER B 241
VAL B 194
None
1.24A 4d9hA-2gezB:
undetectable
4d9hA-2gezB:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 9 SER B 207
GLY B 195
VAL A  56
SER B 241
VAL B 194
None
1.18A 4da6A-2gezB:
undetectable
4da6A-2gezB:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 11 SER B 207
GLY B 195
VAL A  56
SER B 241
VAL B 194
None
1.21A 4danA-2gezB:
undetectable
4danA-2gezB:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 12 SER B 207
GLY B 195
VAL A  56
SER B 241
VAL B 194
None
1.22A 4danA-2gezB:
undetectable
4danB-2gezB:
undetectable
4danA-2gezB:
19.16
4danB-2gezB:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
4 / 8 SER A 100
GLY A  77
THR A  74
GLY B 212
None
0.82A 4fo4B-2gezA:
undetectable
4fo4B-2gezA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 12 ILE A  62
GLY B 195
GLY A  10
ALA A  67
ALA B 208
None
None
None
NA  A 401 (-4.6A)
None
1.01A 4kicB-2gezA:
undetectable
4kicB-2gezA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 9 ALA A  12
GLY B 246
THR B 225
SER B 241
VAL B 254
None
CL  B 406 ( 3.8A)
None
None
None
1.27A 4r20B-2gezA:
undetectable
4r20B-2gezA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
2gez L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
3 / 3 ARG B 308
THR B 304
TRP B 322
None
1.12A 4ug5A-2gezB:
undetectable
4ug5A-2gezB:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)
2gez L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
3 / 3 ARG B 308
THR B 304
TRP B 322
None
1.19A 4uglA-2gezB:
undetectable
4uglA-2gezB:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eeuC-2gezB:
undetectable
5eeuD-2gezB:
undetectable
5eeuC-2gezB:
20.15
5eeuD-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eeuG-2gezB:
undetectable
5eeuH-2gezB:
undetectable
5eeuG-2gezB:
20.15
5eeuH-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eeuL-2gezB:
undetectable
5eeuV-2gezB:
undetectable
5eeuL-2gezB:
20.15
5eeuV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eeuM-2gezB:
undetectable
5eeuN-2gezB:
undetectable
5eeuM-2gezB:
20.15
5eeuN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eeuP-2gezB:
undetectable
5eeuQ-2gezB:
undetectable
5eeuP-2gezB:
20.15
5eeuQ-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eeuR-2gezB:
undetectable
5eeuS-2gezB:
undetectable
5eeuR-2gezB:
20.15
5eeuS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eeuS-2gezB:
undetectable
5eeuT-2gezB:
undetectable
5eeuS-2gezB:
20.15
5eeuT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eeuT-2gezB:
undetectable
5eeuU-2gezB:
undetectable
5eeuT-2gezB:
20.15
5eeuU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eeuU-2gezB:
undetectable
5eeuV-2gezB:
undetectable
5eeuU-2gezB:
20.15
5eeuV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eevC-2gezB:
undetectable
5eevD-2gezB:
undetectable
5eevC-2gezB:
20.15
5eevD-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eevG-2gezB:
undetectable
5eevH-2gezB:
undetectable
5eevG-2gezB:
20.15
5eevH-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eevM-2gezB:
undetectable
5eevN-2gezB:
undetectable
5eevM-2gezB:
20.15
5eevN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eevP-2gezB:
undetectable
5eevQ-2gezB:
undetectable
5eevP-2gezB:
20.15
5eevQ-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eevR-2gezB:
undetectable
5eevS-2gezB:
undetectable
5eevR-2gezB:
20.15
5eevS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eevS-2gezB:
undetectable
5eevT-2gezB:
undetectable
5eevS-2gezB:
20.15
5eevT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eevT-2gezB:
undetectable
5eevU-2gezB:
undetectable
5eevT-2gezB:
20.15
5eevU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eevU-2gezB:
undetectable
5eevV-2gezB:
undetectable
5eevU-2gezB:
20.15
5eevV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eewC-2gezB:
undetectable
5eewD-2gezB:
undetectable
5eewC-2gezB:
20.15
5eewD-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eewG-2gezB:
undetectable
5eewH-2gezB:
undetectable
5eewG-2gezB:
20.15
5eewH-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.35A 5eewM-2gezB:
undetectable
5eewN-2gezB:
undetectable
5eewM-2gezB:
20.15
5eewN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eewP-2gezB:
undetectable
5eewQ-2gezB:
undetectable
5eewP-2gezB:
20.15
5eewQ-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eewR-2gezB:
undetectable
5eewS-2gezB:
undetectable
5eewR-2gezB:
20.15
5eewS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eewS-2gezB:
undetectable
5eewT-2gezB:
undetectable
5eewS-2gezB:
20.15
5eewT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eewT-2gezB:
undetectable
5eewU-2gezB:
undetectable
5eewT-2gezB:
20.15
5eewU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eewU-2gezB:
undetectable
5eewV-2gezB:
undetectable
5eewU-2gezB:
20.15
5eewV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eexC-2gezB:
undetectable
5eexD-2gezB:
undetectable
5eexC-2gezB:
20.15
5eexD-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eexG-2gezB:
undetectable
5eexH-2gezB:
undetectable
5eexG-2gezB:
20.15
5eexH-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eexA-2gezB:
undetectable
5eexK-2gezB:
undetectable
5eexA-2gezB:
20.15
5eexK-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eexL-2gezB:
undetectable
5eexV-2gezB:
undetectable
5eexL-2gezB:
20.15
5eexV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eexM-2gezB:
undetectable
5eexN-2gezB:
undetectable
5eexM-2gezB:
20.15
5eexN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eexP-2gezB:
undetectable
5eexQ-2gezB:
undetectable
5eexP-2gezB:
20.15
5eexQ-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eexR-2gezB:
undetectable
5eexS-2gezB:
undetectable
5eexR-2gezB:
20.15
5eexS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eexS-2gezB:
undetectable
5eexT-2gezB:
undetectable
5eexS-2gezB:
20.15
5eexT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eexT-2gezB:
undetectable
5eexU-2gezB:
undetectable
5eexT-2gezB:
20.15
5eexU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eexU-2gezB:
undetectable
5eexV-2gezB:
undetectable
5eexU-2gezB:
20.15
5eexV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eeyC-2gezB:
undetectable
5eeyD-2gezB:
undetectable
5eeyC-2gezB:
20.15
5eeyD-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eeyG-2gezB:
undetectable
5eeyH-2gezB:
undetectable
5eeyG-2gezB:
20.15
5eeyH-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eeyL-2gezB:
undetectable
5eeyV-2gezB:
undetectable
5eeyL-2gezB:
20.15
5eeyV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eeyM-2gezB:
undetectable
5eeyN-2gezB:
undetectable
5eeyM-2gezB:
20.15
5eeyN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eeyP-2gezB:
undetectable
5eeyQ-2gezB:
undetectable
5eeyP-2gezB:
20.15
5eeyQ-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eeyR-2gezB:
undetectable
5eeyS-2gezB:
undetectable
5eeyR-2gezB:
20.15
5eeyS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eeyS-2gezB:
undetectable
5eeyT-2gezB:
undetectable
5eeyS-2gezB:
20.15
5eeyT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eeyT-2gezB:
undetectable
5eeyU-2gezB:
undetectable
5eeyT-2gezB:
20.15
5eeyU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eeyU-2gezB:
undetectable
5eeyV-2gezB:
undetectable
5eeyU-2gezB:
20.15
5eeyV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eezC-2gezB:
undetectable
5eezD-2gezB:
undetectable
5eezC-2gezB:
20.15
5eezD-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eezG-2gezB:
undetectable
5eezH-2gezB:
undetectable
5eezG-2gezB:
20.15
5eezH-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 8 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eezL-2gezB:
undetectable
5eezV-2gezB:
undetectable
5eezL-2gezB:
20.15
5eezV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eezM-2gezB:
undetectable
5eezN-2gezB:
undetectable
5eezM-2gezB:
20.15
5eezN-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eezP-2gezB:
undetectable
5eezQ-2gezB:
undetectable
5eezP-2gezB:
20.15
5eezQ-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5eezR-2gezB:
undetectable
5eezS-2gezB:
undetectable
5eezR-2gezB:
20.15
5eezS-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5eezS-2gezB:
undetectable
5eezT-2gezB:
undetectable
5eezS-2gezB:
20.15
5eezT-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5eezT-2gezB:
undetectable
5eezU-2gezB:
undetectable
5eezT-2gezB:
20.15
5eezU-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5eezU-2gezB:
undetectable
5eezV-2gezB:
undetectable
5eezU-2gezB:
20.15
5eezV-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef0C-2gezB:
undetectable
5ef0D-2gezB:
undetectable
5ef0C-2gezB:
20.15
5ef0D-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef0G-2gezB:
undetectable
5ef0H-2gezB:
undetectable
5ef0G-2gezB:
20.15
5ef0H-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef0A-2gezB:
undetectable
5ef0K-2gezB:
undetectable
5ef0A-2gezB:
20.15
5ef0K-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5ef0L-2gezB:
undetectable
5ef0V-2gezB:
undetectable
5ef0L-2gezB:
20.15
5ef0V-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef0M-2gezB:
undetectable
5ef0N-2gezB:
undetectable
5ef0M-2gezB:
20.15
5ef0N-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef0P-2gezB:
undetectable
5ef0Q-2gezB:
undetectable
5ef0P-2gezB:
20.15
5ef0Q-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef0R-2gezB:
undetectable
5ef0S-2gezB:
undetectable
5ef0R-2gezB:
20.15
5ef0S-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef0S-2gezB:
undetectable
5ef0T-2gezB:
undetectable
5ef0S-2gezB:
20.15
5ef0T-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef0T-2gezB:
undetectable
5ef0U-2gezB:
undetectable
5ef0T-2gezB:
20.15
5ef0U-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5ef0U-2gezB:
undetectable
5ef0V-2gezB:
undetectable
5ef0U-2gezB:
20.15
5ef0V-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef1C-2gezB:
undetectable
5ef1D-2gezB:
undetectable
5ef1C-2gezB:
20.15
5ef1D-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef1G-2gezB:
undetectable
5ef1H-2gezB:
undetectable
5ef1G-2gezB:
20.15
5ef1H-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 8 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5ef1L-2gezB:
undetectable
5ef1V-2gezB:
undetectable
5ef1L-2gezB:
20.15
5ef1V-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef1M-2gezB:
undetectable
5ef1N-2gezB:
undetectable
5ef1M-2gezB:
20.15
5ef1N-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef1P-2gezB:
undetectable
5ef1Q-2gezB:
undetectable
5ef1P-2gezB:
20.15
5ef1Q-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef1R-2gezB:
undetectable
5ef1S-2gezB:
undetectable
5ef1R-2gezB:
20.15
5ef1S-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef1S-2gezB:
undetectable
5ef1T-2gezB:
undetectable
5ef1S-2gezB:
20.15
5ef1T-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef1T-2gezB:
undetectable
5ef1U-2gezB:
undetectable
5ef1T-2gezB:
20.15
5ef1U-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5ef1U-2gezB:
undetectable
5ef1V-2gezB:
undetectable
5ef1U-2gezB:
20.15
5ef1V-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef2C-2gezB:
undetectable
5ef2D-2gezB:
undetectable
5ef2C-2gezB:
20.15
5ef2D-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef2G-2gezB:
undetectable
5ef2H-2gezB:
undetectable
5ef2G-2gezB:
20.15
5ef2H-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 8 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5ef2L-2gezB:
undetectable
5ef2V-2gezB:
undetectable
5ef2L-2gezB:
20.15
5ef2V-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef2M-2gezB:
undetectable
5ef2N-2gezB:
undetectable
5ef2M-2gezB:
20.15
5ef2N-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef2P-2gezB:
undetectable
5ef2Q-2gezB:
undetectable
5ef2P-2gezB:
20.15
5ef2Q-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef2R-2gezB:
undetectable
5ef2S-2gezB:
undetectable
5ef2R-2gezB:
20.15
5ef2S-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef2S-2gezB:
undetectable
5ef2T-2gezB:
undetectable
5ef2S-2gezB:
20.15
5ef2T-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef2T-2gezB:
undetectable
5ef2U-2gezB:
undetectable
5ef2T-2gezB:
20.15
5ef2U-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5ef2U-2gezB:
undetectable
5ef2V-2gezB:
undetectable
5ef2U-2gezB:
20.15
5ef2V-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef3C-2gezB:
undetectable
5ef3D-2gezB:
undetectable
5ef3C-2gezB:
20.15
5ef3D-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef3G-2gezB:
undetectable
5ef3H-2gezB:
undetectable
5ef3G-2gezB:
20.15
5ef3H-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef3A-2gezB:
undetectable
5ef3K-2gezB:
undetectable
5ef3A-2gezB:
20.15
5ef3K-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 9 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.35A 5ef3M-2gezB:
undetectable
5ef3N-2gezB:
undetectable
5ef3M-2gezB:
20.15
5ef3N-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef3P-2gezB:
undetectable
5ef3Q-2gezB:
undetectable
5ef3P-2gezB:
20.15
5ef3Q-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.38A 5ef3R-2gezB:
undetectable
5ef3S-2gezB:
undetectable
5ef3R-2gezB:
20.15
5ef3S-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.36A 5ef3S-2gezB:
undetectable
5ef3T-2gezB:
undetectable
5ef3S-2gezB:
20.15
5ef3T-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.37A 5ef3T-2gezB:
undetectable
5ef3U-2gezB:
undetectable
5ef3T-2gezB:
20.15
5ef3U-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
5 / 10 GLY B 195
HIS A   9
ALA A  67
THR B 225
THR B 209
None
None
NA  A 401 (-4.6A)
None
None
1.40A 5ef3U-2gezB:
undetectable
5ef3V-2gezB:
undetectable
5ef3U-2gezB:
20.15
5ef3V-2gezB:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)
2gez L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
3 / 3 ARG B 308
THR B 304
TRP B 322
None
1.12A 5g6cA-2gezB:
undetectable
5g6cA-2gezB:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_C_IPHC101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus;
Lupinus
luteus)
4 / 5 ILE B 289
CYH B 196
LEU A  59
HIS A   9
None
1.14A 5hrqC-2gezB:
undetectable
5hrqD-2gezB:
undetectable
5hrqL-2gezB:
undetectable
5hrqC-2gezB:
19.51
5hrqD-2gezB:
12.03
5hrqL-2gezB:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)
2gez L-ASPARAGINASE ALPHA
SUBUNIT
L-ASPARAGINASE BETA
SUBUNIT

(Lupinus
luteus)
5 / 12 GLY B 213
GLY B 212
GLY B 229
HIS A   9
PRO A 105
CL  B 406 (-3.7A)
None
None
None
None
1.02A 6gngB-2gezB:
undetectable
6gngB-2gezB:
14.48