SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2gf5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HM1_B_J3ZB1_1 (ESTROGEN RECEPTOR)	2gf5	FADD PROTEIN (Homo sapiens)	5 / 11	LEU A 8 LEU A 7 LEU A 67 GLY A 42 LEU A 43	None	1.28A	3hm1B-2gf5A: undetectable	3hm1B-2gf5A: 24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K39_O_BCZO1001_0 (NEURAMINIDASE)	2gf5	FADD PROTEIN (Homo sapiens)	5 / 12	GLU A 19 LEU A 15 ARG A 71 ARG A 72 GLU A 22	None	1.23A	3k39O-2gf5A: undetectable	3k39O-2gf5A: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWV_A_BCZA513_0 (NEURAMINIDASE)	2gf5	FADD PROTEIN (Homo sapiens)	5 / 12	GLU A 19 LEU A 15 ARG A 71 ARG A 72 GLU A 22	None	1.25A	4mwvA-2gf5A: undetectable	4mwvA-2gf5A: 17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MX0_A_BCZA513_0 (NEURAMINIDASE)	2gf5	FADD PROTEIN (Homo sapiens)	5 / 12	GLU A 19 LEU A 15 ARG A 71 ARG A 72 GLU A 22	None	1.27A	4mx0A-2gf5A: undetectable	4mx0A-2gf5A: 17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZME_A_ADNA1002_1 (MYOSIN HEAVY CHAIN KINASE A)	2gf5	FADD PROTEIN (Homo sapiens)	5 / 11	GLY A 85 LEU A 63 LEU A 8 PHE A 4 THR A 60	None	1.11A	4zmeA-2gf5A: undetectable	4zmeA-2gf5A: 18.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3HM1_B_J3ZB1_1","ESTROGEN RECEPTOR","2gf5","FADD PROTEIN","Homo sapiens",5,"LEU A   8;LEU A   7;LEU A  67;GLY A  42;LEU A  43","None","1.28A","3hm1B-2gf5A:undetectable","3hm1B-2gf5A:24.51"],["3K39_O_BCZO1001_0","NEURAMINIDASE","2gf5","FADD PROTEIN","Homo sapiens",5,"GLU A  19;LEU A  15;ARG A  71;ARG A  72;GLU A  22","None","1.23A","3k39O-2gf5A:undetectable","3k39O-2gf5A:18.67"],["4MWV_A_BCZA513_0","NEURAMINIDASE","2gf5","FADD PROTEIN","Homo sapiens",5,"GLU A  19;LEU A  15;ARG A  71;ARG A  72;GLU A  22","None","1.25A","4mwvA-2gf5A:undetectable","4mwvA-2gf5A:17.27"],["4MX0_A_BCZA513_0","NEURAMINIDASE","2gf5","FADD PROTEIN","Homo sapiens",5,"GLU A  19;LEU A  15;ARG A  71;ARG A  72;GLU A  22","None","1.27A","4mx0A-2gf5A:undetectable","4mx0A-2gf5A:17.27"],["4ZME_A_ADNA1002_1","MYOSIN HEAVY CHAIN KINASE A","2gf5","FADD PROTEIN","Homo sapiens",5,"GLY A  85;LEU A  63;LEU A   8;PHE A   4;THR A  60","None","1.11A","4zmeA-2gf5A:undetectable","4zmeA-2gf5A:18.33"]]